AbbVie · 19 hours ago
Principal Research Scientist II, Analytical Development
Worcester, MA
Full-time
Onsite
Lead/Staff
8+ years expAbbVie is a company dedicated to discovering and delivering innovative medicines. They are seeking a Principal Scientist II in Analytical Development to guide the biophysical analytical strategy and develop novel analytical methods for characterizing mRNA-based targeted lipid nanoparticles.
BiotechnologyFinanceHealthcarePharmaceuticalVenture CapitalFinancial ServicesHealth CareMedical
Responsibilities
Lead strategy for and development of novel biophysical methods to characterize tLNP drug product and protein components, including but not limited to LC/CE/MS, DLS, MALLS, Nano flow cytometry, mass photometry, BLI, and plate-based assays
Design and lead structure-activity relationship and extended characterization studies to improve tLNP function and stability
Support product characterization for tLNP platform/formulation development and lead candidate selection
Establish automation/lipid chromohigh throughput (HTP) workflows and in-process analytical methods for routine and non-routine testing of the tLNP pipeline
Represent functional area in cross-functional pipeline and technology development teams. Effectively communicate complex technical topics to collaborators and management
Support method transfer and qualifications as needed
Manage and develop a team of 2-5 scientists
Draft technical reports and documents as needed
Qualification
Required
Bachelor's Degree in Science related field with 16 years of related work; Master's Degree Science or PharmD with 14 years of related work; PhD in Science or related field with 8 years of related work experience
Four years of experience managing direct reports and/or a functional team
Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with proven technical and leadership track record developing analytical characterization methods for nanoparticles (e.g. LNPs, viral vectors, etc) and biologics (e.g. antibodies, mRNA, etc) is required
Experience developing analytical methods for nanoparticles (e.g. nano flow cytometry, mass photometry, NTA, AUC, etc.) and biologics (e.g. LC, CE, iCIEF, MS, MALLS, BLI, etc) is required
Strong proficiency authoring and reviewing technical reports
Exceptional communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments
Preferred
Experience with method transfer and qualification is preferred
Familiarity with international regulatory standards and application to phase-appropriate analytical development and strategy is preferred
Experience designing and executing stability and comparability studies is preferred
Benefits
Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Short-term incentive programs
Company
AbbVie
AbbVie is a biopharmaceutical company focused on immunology, oncology, neuroscience, virology, and aesthetics. It is a sub-organization of AbbVie.
10001+ employees
H1B Sponsorship
AbbVie has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (273)
2024 (190)
2023 (225)
2022 (284)
2021 (186)
2020 (186)
Funding
Current Stage
Public CompanyTotal Funding
$15B2024-02-27Post Ipo Debt· $15B
2023-03-08Post Ipo Equity· $0.25M
2012-12-20IPO
Leadership Team
Robert Michael
Chairman of the Board and Chief Executive Officer
Micah Bregman
Vice President, Global Strategy and Pipeline, Allergan Aesthetics
Recent News
2026-02-12
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2026-02-12
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