Atrium · 1 day ago
Principal Scientist (ADME) - 160216
Boston, MA
Full-time
Onsite
Senior Level, Lead/Staff
$70/hr - $80/hr
5+ years expAtrium is a people-centric organization that values collaboration and innovation. They are seeking a Principal Scientist (ADME) to develop and execute advanced in vitro ADME assays, supporting accelerated drug discovery through high-quality data delivery for lead optimization.
Real Estate
Responsibilities
Develop, optimize, and validate high-throughput in vitro ADME assays covering solubility, permeability, protein binding, metabolic stability, and enzyme inhibition/induction
Utilize automated liquid handling systems for assay automation and screening
Perform and troubleshoot mass spectrometry analyses, including method development
Manage sample preparation and conduct data analysis to calculate pharmacokinetic parameters
Communicate results and provide recommendations to cross-functional project teams
Maintain laboratory documentation and ensure compliance with quality and safety standards
Qualification
Required
Ph.D. (2+ years industry experience) or Master's degree (5+ years industry experience) in Pharmaceutical Sciences, Pharmacology, Analytical Chemistry, or related field
Hands-on experience with LC-MS or acoustic mass spectrometry in high-throughput settings
Proven ability in automated in vitro ADME assay development
Strong knowledge of drug metabolism pathways and DMPK
Familiarity with ADME prediction and data visualization tools
Preferred
Experience with laboratory automation and electronic data capture systems
Programming skills (e.g., Python, R) and data visualization expertise
Experience with clinical sample handling and CRO environments
Benefits
Medical, dental, and vision insurance.
401(k) plan.
Holiday pay and sick time.
Additional comprehensive benefits offerings.
Company
Atrium
Atrium is a global WBENC-certified Talent Solutions and Extended Workforce Management leader.
201-500 employees
H1B Sponsorship
Atrium has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (2)
2020 (4)
Funding
Current Stage
Growth StageLeadership Team
Caylon Joiner
Talent Acquisition Partner
Shannon Mooney
Managing Director, Strategic Partnerships
Company data provided by crunchbase