4D Molecular Therapeutics · 15 hours ago
Senior Infrastructure and Security Engineer
Emeryville, CA
Full-time
Onsite
Mid, Senior Level
3+ years exp4D Molecular Therapeutics is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics. They are seeking a highly skilled and experienced Senior Infrastructure and Security Engineer to ensure the seamless operation, scalability, and security of their IT infrastructure, enterprise end-user services, and cloud environments.
BiotechnologyLife ScienceGenetics
Responsibilities
Plan, design, develop, and implement scalable, secure, and user-focused hybrid IT solutions, including world-class infrastructure, Cloud, high-end workstations, desktops, laptops, mobile devices (secure BYOD)
Manage virtualization technologies (e.g., VDI/VM) to enable flexible work arrangements
Deploy and configure Windows, macOS, and Linux operating systems to ensure compatibility, performance, and compliance with security standards
Administer and support Active Directory environments, including Group Policy management, user accounts, and domain controller maintenance
Maintain and optimize Windows Server and Linux systems, ensuring high availability, security, and performance
Support Google Cloud Platform (GCP) infrastructure, including compute, storage, and networking services, while leveraging GCP tools for monitoring, security, and cost optimization
Implement and maintain system images, software packages, and productivity/business applications
Develop and manage automation scripts and workflows to optimize operations, enhance user experience, and increase efficiency
Build comprehensive automated infrastructure management solutions, including configuration management, monitoring, and analytics, to improve operational efficiency and reliability
Continuously identify opportunities for automation and process improvement, driving innovation and operational excellence
Proactively monitor system performance and ensure high availability, reliability, and scalability
Rapidly troubleshoot and resolve hardware, software, and system issues, including those related to Active Directory, Windows, Linux, and GCP environments
Implement and maintain cybersecurity controls for infrastructure and endpoints, including vulnerability management and data loss prevention
Support the detection and response to security incidents, assisting with forensic investigations and remediation
Help develop and update security policies, standards, and procedures for IT infrastructure and end-user services
Participate in risk assessments and contribute to strategies that address information security, business continuity, and compliance requirements
Ensure compliance with regulatory requirements (e.g., SOX, 21 CFR Part 11) and industry best practices
Assist with security awareness initiatives to educate staff on policies and best practices for protecting company assets
Monitor infrastructure security metrics and report on performance to ensure continuous improvement
Provide technical support to end users, resolving issues promptly and effectively
Collaborate with cross-functional IT and security teams, as well as external partners, to assess needs, address emerging threats and vulnerabilities, and integrate technology solutions
Foster strong relationships with stakeholders to align technology solutions with business goals
Evaluate emerging technologies and recommend solutions that align with business objectives and budget constraints
Stay current with industry trends to inform organizational decisions and future-proof solutions
Participate in audits as needed and ensure alignment with IT policies and standards
Perform other duties as assigned, adapting to the dynamic needs of the organization
Qualification
Required
Industry recognized technical level education & experience
3-5 years' experience as user-focus infrastructure engineer delivering solutions in highly regulated, complex and multi-vendor ecosystems with a strong preference for candidates having pharma or biotech industry expertise and a deep understanding of compliance-driven environments
3-5 years' experience managing desktop and server OS and application patching and application packaging using sophisticated management systems (e.g. Intune, System Center Configuration Manager)
3-5 years' experience supporting Windows Enterprise customers in a large-scale (300+ node) environment
Successful track record of infrastructure architecture and administration, execution, and delivery
Ability to multi-task in a fast-paced, dynamic environment
Experience working in a regulated networking environment (SOX and 21CFR11)
Excellent organizational, communication and customer service skills with active-listening skills
Proven adaptability to shifting project schedules, priorities, and assignments; able to make effective decisions under pressure
Demonstrated problem-solver with the ability to cope under pressure and coordinate multiple activities in a dynamic, fast-paced team environment
Excellent written and documentation skills including proof reading and attention to detail
Hands-on experience with hardware and software troubleshooting, system imaging, and software deployment tools
Must be a self-driven, motivated IT professional with strong analytical and problem-solving skills, and ability to diagnose and resolve complex technical issues
Excellent communication and interpersonal skills, with the ability to work effectively in a team environment and interact with diverse stakeholders including executive management
Proactively identify opportunities for process improvements and automation to streamline end-user support services
Proficient in automation technologies, including Pipeline Pilot, MS Power Automate and additional scripting languages, with a strong ability to leverage scripting expertise to streamline processes, enhance efficiency, and drive operational excellence
Demonstrate extensive expertise in Google Cloud Platform (GCP) and Azure, including advanced security, monitoring, automation, and optimization of cloud infrastructure
Comprehensive expertise in operating systems (Windows, macOS, Linux), virtualization technologies (e.g., VMware, Citrix Virtual Apps and Desktops), and endpoint management solutions (e.g., Microsoft Intune, SCCM, Tanium), M365, Okta, Active Directory, etc
Strong hands-on experience with Active Directory, Windows, Linux, Google Cloud Platform (GCP), and Azure
5+ years biopharmaceutical experience in fast-growing environment
Office environment with daily onsite presence required
Daily onsite presence in an office environment
Proven ability to adapt to shifting priorities while maintaining attention to detail and delivering high-quality results
Preferred
CISSP or GCP Certification preferred
Company
4D Molecular Therapeutics
4D Molecular Therapeutics designs, develops, and commercializes transformative gene therapeutic products for unmet medical conditions.
51-200 employees
H1B Sponsorship
4D Molecular Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (3)
2023 (1)
2022 (1)
2021 (4)
Funding
Current Stage
Public CompanyTotal Funding
$702.5MKey Investors
Cystic Fibrosis FoundationViking Global Investors
2025-11-06Post Ipo Equity· $100M
2025-10-13Post Ipo Equity· $7.5M
2024-02-06Post Ipo Equity· $300M
Leadership Team
David Kirn
Co-Founder & CEO
L
Liansheng Zhu
Sr VP Biometrics and Data Quality
Recent News
2026-01-07
Longevity.Technology - Latest News, Opinions, Analysis and Research
2025-12-19
Benzinga.com
2025-12-19
Company data provided by crunchbase