Ellison Medical Institute · 1 day ago
Senior AI Peptide and Protein Design Engineer
Los Angeles, CA
Full-time
Onsite
Senior Level
$160K/yr - $213K/yr
5+ years expThe Ellison Medical Institute is dedicated to advancing health and cancer care through innovative research and technology. They are seeking a Senior AI Peptide and Protein Design Engineer to lead the development of AI-driven peptide and protein engineering capabilities and collaborate with experts to shape the initiative's direction.
Biotechnology
Responsibilities
Develop, deploy, and continuously improve computational pipelines for de novo peptide and protein design, including property prediction using data-driven and modeling approaches. Define robust benchmarking, performance metrics, and validation strategies
Design and optimize novel peptide and protein therapeutics using sequence- and structure-based computational design methods, leveraging silico predictions to support lead identification and optimization
Work directly with the peptide and protein production and characterization teams to experimentally test designs, interpret results, and incorporate feedback into iterative design cycles
Collaborate with target biology and translational research teams to evaluate designs in biological context and support progression from concept to optimized lead candidates
Mentoring junior scientists or contributing to hiring and team growth
Maintain clear, reproducible documentation of methodologies, code, and results. Communicate findings effectively to scientific and leadership stakeholders
Contribute to a high-performing scientific culture that values rigor, innovation, transparency, collaboration, accountability, and efficient execution
Qualification
Required
Ph.D. in Computational Peptide/Protein Design, Structural Biology, Protein Engineering, or a closely related field
Postdoctoral or industry experience applying computational modeling to peptide or protein engineering, and a strong publication record or proven track record contributing to therapeutic development
5+ years of hands-on experience in peptide and protein design, modeling, and sequence/structure-function prediction, with proficiency in relevant macromolecular modeling software (i.e. AlphaFold, RoseTTAFold, RFdiffusion, RFpeptides, Boltz, ProteinMPNN)
Demonstrated understanding of peptide and protein biology, including structure, folding, stability, and experimental constraints, gained through direct experimental work and/or close collaboration with wet-lab teams
Strong analytical and problem-solving skills applied to complex biological and computational challenges
Excellent teamwork, time management, documentation, and communication skills
Proven ability to work effectively in interdisciplinary, cross-functional research environments
Benefits
Bonus eligibility
Comprehensive benefits package
Company
Ellison Medical Institute
Formerly known as the Ellison Institute of Technology Los Angeles, the Ellison Medical Institute strives to spark innovation, leverage technology, and drive interdisciplinary, patient-centered research to continually enhance health, reimagine and redefine cancer care, and transform lives.
51-200 employees
H1B Sponsorship
Ellison Medical Institute has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (6)
2024 (2)
2022 (1)
2021 (4)
Funding
Current Stage
Growth StageLeadership Team
L
Lisa Flashner
Senior Strategic Advisor
Recent News
businessweekly.co.uk
2025-04-11
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