Thermo Fisher Scientific · 13 hours ago
Scientist, Purification Process
Thermo Fisher Scientific is a leading global contract research organization focused on serving science. They are seeking a Scientist for Purification Process to support protein purification process development and optimization for therapeutic monoclonal antibody products throughout clinical trials.
Research
Responsibilities
Conduct routine protein purification to support formulation team’s material needs and cell culture development
Conduct high-throughput protein purification to support cell line development
Provide assistance in purification process development, optimization, and scale-up manufacturing
Conduct routine analyses of in-process samples using relevant product purity and process impurity analytical tools
Prepare buffers and solutions needed for laboratory work
Present work summary in the group meeting
Write routine electronic laboratory notebook
Other responsibilities as assigned
Qualification
Required
Must be legally authorized to work in the United States without sponsorship
Must be able to pass a comprehensive background check, which includes a drug screening
BS degree in biochemistry, bioengineering, biology, chemistry or related fields, preferably with some relevant industry experiences with 2-4 years of experience or MS in above fields with 1-2 years of experience
Good knowledge in protein chemistry and bioprocessing
Good knowledge and hands-on experiences in various types of column/membrane chromatography (affinity, size exclusion, ion exchanges, multi-mode) and filtration technology; TFF
Experiences in using AKTA line of purification instruments
Experiences in using ultrafiltration/diafiltration instrument for buffer exchange, product concentration, and formulation
Aseptic Technique
Good verbal and written communication skills, organized, cooperative, independent, meticulous
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner
Able to work upright and stationary and/or standing for typical working hours
Able to lift and move objects up to 25 pounds
Able to work in non-traditional work environments
Able to use and learn standard office equipment and technology with proficiency
May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments
Able to perform successfully under pressure while prioritizing and handling multiple projects or activities
Preferred
Experiences in protein analysis such as HPLC, CGE, ELISA, etc. is a plus
Experiences in high-throughput protein purification platform are desirable but not required
Company
Thermo Fisher Scientific
The world leader in serving science To serve science, Thermo Fisher Scientific needs to stay ahead of it, we need to anticipate customer needs.