Thermo Fisher Scientific · 16 hours ago
Small-Scale Purification Scientist
Plainville, Massachusetts, USA
Full-time
Onsite
Mid Level
$96K/yr - $127K/yr
3+ years expThermo Fisher Scientific is a leader in the life sciences sector, and they are seeking a Small-Scale Purification Scientist to join their Bioprocess Design Center. This role involves designing, executing, and documenting downstream purification experiments to support the development of single-use purification technologies.
Research
Responsibilities
Execute purification resin design studies for internal and external customers using Thermo Fishers brand resins
Independently design and execute small-scale downstream purification experiments spanning capture, intermediate, and polishing operations
Develop experimental plans aligned to defined technical objectives, including appropriate controls, success criteria, and data quality expectations
Execute chromatography and filtration processes (e.g., column screening, process optimization, UF/DF) with a focus on Thermo Fisher single-use chromatography and centrifugation systems
Troubleshoot experimental issues and drive resolution with minimal supervision
Apply systems-level thinking to understand how downstream purification integrates with upstream processes, automation, analytics, and overall workflow design
Support evaluation of single-use purification technologies, process configurations, and operating strategies
Identify operational risks, constraints, and improvement opportunities during experimental execution
Analyze experimental data, identify trends, and draw scientifically defensible conclusions
Author protocols, technical reports, summaries, and SOPs suitable for internal use and customer-facing communication
Maintain complete, accurate laboratory notebooks and records in accordance with internal data integrity and IP standards
Support customer visits, technical demonstrations, and internal reviews by clearly articulating experimental intent, methods, and results
Communicate progress, risks, and outcomes effectively to both technical and non-technical stakeholders
Maintain a safe, compliant, and well-organized laboratory environment
Follow applicable safety, quality, and training requirements (e.g., GLP, ISO, internal EHS standards)
Contribute to continuous improvement of downstream laboratory workflows and experimental practices
Support preparation of bills of materials and logistical needs for BDC projects and customer activities
Qualification
Required
B.S. in Chemical Engineering, Biochemistry, Biotechnology, Bioengineering, or related field with 3–5 years of relevant downstream experience
M.S. with 2–3 years of relevant experience
Equivalent combinations of education and experience will be considered
Hands-on experience with downstream purification and bioprocessing workflows
Familiarity with selection, setup, and operation of single-use chromatography columns, flow kits, and UF/DF systems
Experience designing and executing controlled experiments; DoE experience preferred
Strong data analysis, documentation, and technical writing skills
Proficiency with standard data analysis and reporting tools (e.g., Excel, PowerPoint)
Ability to work in a laboratory environment and handle light to moderate lifting (up to ~50 lbs)
Standing and walking for extended periods during experimental execution
Manual dexterity to operate laboratory equipment and instrumentation
Preferred
Demonstrated ability to work independently in a fast-paced, matrixed environment
Strong problem-solving skills and attention to detail
Ability to translate experimental data into practical, workflow-relevant insights
Comfort operating in environments with evolving priorities and requirements
Collaborative, customer-centric mindset
Benefits
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
Company
Thermo Fisher Scientific
The world leader in serving science To serve science, Thermo Fisher Scientific needs to stay ahead of it, we need to anticipate customer needs.
10001+ employees
H1B Sponsorship
Thermo Fisher Scientific has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
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Trends of Total Sponsorships
2025 (272)
2024 (224)
2023 (233)
2022 (342)
2021 (315)
2020 (227)
Funding
Current Stage
Late StageLeadership Team
Heather Stewart
HR Business Partner - Global Enterprise Services
Laura Green
Associate Human Resources Business Partner
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