AstraZeneca · 15 hours ago
Scientist, Analytical Sciences
Santa Monica, CA
Full-time
Onsite
Entry, Mid Level
$87K/yr - $131K/yr
2+ years expAstraZeneca is a leading biopharmaceutical company focused on delivering life-changing medicines. The Scientist in Analytical Sciences will develop and optimize genomic assay testing functions to support engineered cell therapy, collaborating with various teams to ensure quality data and operational excellence.
BiotechnologyMedical DeviceHealthcarePharmaceuticalBiopharmaHealth CareMedicalPrecision Medicine
Responsibilities
Lead the development of operational processes & continuous improvement of the genomic function within Analytical Operations
Manage critical reagent inventory, assay control material, and general consumables to maintain team’s capabilities to execute genomic assays
Perform genomic assays including, but not limited to, DNA/RNA extraction, digital PCR, qPCR, and RNP activity assays
Maintain sample identity from sample source to molecular derivatives and its associated results
Coordinate to produce assay control materials with Process Engineers or External Suppliers and characterize material in a timely manner to support routine testing
Lead in the method transfer of genomic assays into the Analytical Operations team by assessing incoming test methods, critical reagents, and training schedule
Collaborate with method & automation developers to optimize methods for high throughput testing and streamline documentation & analysis
Maintain records of executed methods and reported results for samples and assay control material
Monitor assay trending and collaborate with method developers to troubleshoot analytical assays
Expand laboratory and operational skills to support department needs
Provide technical mentorship ensuring scientific rigor and operational excellence in the lab
Maintain laboratory instruments, ensuring calibration, maintenance, and troubleshooting are performed
Qualification
Required
Three (3) years with BS/BA, or two (2) years with MS/MA in immunology, Cell Biology, Oncology, Molecular Biology, or a related discipline with experience in a biotechnology, biopharmaceutical, or academic setting
Strong expertise in genomic assays, especially those pertaining to human sample derivatives, digital PCR, and qPCR
Hands-on experience with media preparations and suspension/adherent culture work: thaw, culture, expand, and cryopreserve
Proficiency in immune cell culture, including primary T cells or engineered immune cells
Proficiency in data analysis and troubleshooting of genomic analytical assays
Proficient knowledge of general cell therapy processes and understanding of sampling and testing points for characterization to support process development
Ability to clearly convey scientific findings and development rationale
Preferred
Experience in flow cytometry, immunoassay, or cell-based assays is a plus
Working knowledge of protein purification technologies and common analytical methods (e.g., SEC-UPLC, LC-MS, SDS-PAGE, CE)
Familiarity with lab automation scheduling software; Green Button Go preferred
Basic scripting for data handling (e.g., Python, Jupyter) is a plus, not required
Exposure to imaging or flow cytometry platforms and analysis tools (iQue, Attune, FlowJo) is beneficial for specific assays but not central to the role
Benefits
Short-term incentive bonus opportunity
Eligibility to participate in our equity-based long-term incentive program (salaried roles)
To receive a retirement contribution (hourly roles)
Commission payment eligibility (sales roles)
Company
AstraZeneca
AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.
10001+ employees
H1B Sponsorship
AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (2)
2020 (11)
Funding
Current Stage
Public CompanyTotal Funding
$5.26B2024-07-30Post Ipo Debt· $1.51B
2023-02-28Post Ipo Debt· $2.25B
2023-02-24Post Ipo Debt· $1.5B
Leadership Team
Pascal Soriot
Executive Director and Chief Executive Officer
Aradhana Sarin
Group CFO and Executive Director
Recent News
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