Naderi Engineering, Inc. · 10 hours ago
System Engineer - Molecular Sequencing
Santa Clara, CA
Contract
Onsite
Mid, Senior Level
$37/hr - $70/hr
1+ years expNaderi Engineering, Inc. is seeking a passionate Systems Engineer to join their Systems Development Group to support the Next Generation Sequencing (NGS) products. The role involves hands-on contributions in the feasibility, development, customer support, and integration phases of NGS solutions, while maintaining detailed documentation throughout all phases of research and development.
BiotechnologyNuclearProject Management
Hiring Manager
Ali Naderi
Responsibilities
Become an expert on the operation of the Roche Single Molecule Sequencing Platform
Perform a variety of sample prep, library, or sequencing and sequencing related experiments on a daily basis, help to analyze and interpret the data
General support of diverse research and development activities
Customer support activities such as monitoring runs, documenting and communicating defects, and following escalation paths to resolve customer issues
Contribute to the platform verification team as a member by executing, analyzing, and interpreting the results of platform verification studies
Perform all work using best laboratory practices and maintain a well-organized and concise record of work performed and progress made
Assist engineers with hardware design through testing subcomponents
Analyze data, derive conclusions, document findings, write SOPs and prepare reports for sharing within and between R&D groups
Setup strong experimental designs while working independently
Troubleshoot instrument failures and seek out specialized help as needed
Develop and deploy a wide range of technologies, including sample extraction, library prep, and sequencing
Develop, execute, and document test cases for verification and validation. Ensures complete and comprehensive coverage of requirements in the test campaigns
Customer support through monitoring of runs, early morning meetings to discuss defects, results and progress, QC of reagents and configuration used for customer, possible travel to customer sites
Support of instrument fleet to learn troubleshooting techniques as needed to assist R&D and to support customers
Perform system integration and testing activities and verify system performance through simulation, tests, and measurements. Assess results for applicability, validity, and conformance to product requirements
Work independently with general management direction to drive product development and collaborations to identify opportunities for continuous improvement
Keep supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas
Qualification
Required
B.S. or M.S. or PhD degree in the science/chemistry/engineering required and 1-5 years of experience (depending on educational background)
Previous laboratory experience required
Familiarity with MATLAB, GIT, Python or similar tools for data analysis and/or automation
Previous experience with PCR required
Excellent written and oral communication skills are essential
Demonstrated ability to work well in teams and across scientific disciplines is essential
The candidate should be passionate, self-motivated, and possess a strong desire to acquire on-the-job training
Hands-on PCR experience required (must be able to explain principles, controls, and troubleshooting)
Prior laboratory experience with nucleic acid handling and contamination control
Strong written and oral communication skills
Preferred
Candidates with hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing are encouraged to apply
Previous experience with prototype instruments or DNA sequencing desirable
Experience with a variety of laboratory devices and instrumentation, including PCR and automation
3+ years of hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing
Knowledge in all phases of NGS workflow such as nucleic acid chemistry, and primer design technologies for gene targets is highly desirable
Proven hands-on troubleshooting experience and skills in wet bench workflows on NGS platform
Experience with statistical tools (e.g. Python/JMP for regression analysis, ANOVA) and Design of Experiments methodology, application of statistical process control is essential
Experience in implementing workflow on semiconductor-based sensing devices or microfluidic devices is desirable
Knowledge in surface chemistry is also desirable
Familiarity with Illumina or similar sequencing platforms
Background in assay development, troubleshooting, or prototype instrumentation
Knowledge of statistical analysis (DOE, ANOVA, SPC) is a plus
Company
Naderi Engineering, Inc.
Naderi Engineering, Inc.
11-50 employees
Funding
Current Stage
Early StageCompany data provided by crunchbase