Crinetics Pharmaceuticals · 10 hours ago
Principal Platform and Data Architect
San Diego, CA
Full-time
Onsite
Lead/Staff
$170K/yr - $213K/yr
15+ years expCrinetics Pharmaceuticals is a pharmaceutical company dedicated to developing therapies for endocrine diseases. They are seeking a Principal Platform and Data Architect to lead the design and development of their enterprise data and AI/ML infrastructure, ensuring data integrity and accessibility to support critical decision-making processes.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Define, own, and execute a comprehensive, forward-looking roadmap for the company’s data, analytics, and AI/ML platforms, with a strong emphasis on the Microsoft Azure ecosystem
Excel at understanding and interpreting complex business questions and insights. Map these business needs to the specific data required and architect and build the end-to-end data pipelines and solutions to deliver answers
Lead the hands-on design, development, and implementation of a scalable and secure infrastructure for our AI and machine learning models. Actively build, code, and configure foundational components of the data platform
Serve as the foremost expert on Microsoft Azure data platforms. Design, build, and manage solutions leveraging Azure Databricks, Azure Synapse Analytics, Azure Data Lake Storage, Azure Data Factory, and other related services
Lead the evaluation and profiling of various source data systems. Architect and implement robust, scalable solutions to consume, ingest, and prepare data for subsequent machine learning, AI, and advanced reporting use cases
Partner with data scientists, machine learning engineers, software developers, and business leaders to gather requirements, identify opportunities for improvement, and ensure architectural alignment across projects
Work closely with managed service partners and technology vendors, providing clear architectural direction and oversight to ensure their work aligns with our technical standards, roadmap, and business objectives
Establish and enforce best practices for data management, data governance, and data security. Ensure all data solutions are designed and built with scalability, reliability, and cost-effectiveness in mind
Act as a senior individual contributor and technical authority. Influence the technical direction of projects by building proof-of-concepts, setting high standards for code and design, and providing technical guidance to peers across the technology team
Qualification
Required
Bachelor's degree in Computer Science, Engineering, or a related field; Master's degree preferred
15+ years of experience in data architecture, data engineering, or platform engineering, with at least 5 years in a senior or principal architect role
Expert-level knowledge and hands-on experience building complex data pipelines and infrastructure within the Microsoft Azure cloud platform
Proven experience designing, building, and deploying production-level solutions with Azure Databricks, including a deep understanding of its architecture, security, and performance tuning
Demonstrated ability to translate ambiguous business requirements into concrete technical designs and then personally build and deliver those data solutions
Extensive hands-on experience with data profiling, data modeling, ETL/ELT development, and data warehousing concepts
Strong, current understanding of the infrastructure and tooling required to support the full lifecycle of AI and machine learning models
Experience architecting and personally contributing to the build of large-scale, high-performance data pipelines
Excellent analytical and problem-solving skills, with the ability to think strategically about business, product, and technical challenges
Exceptional communication and interpersonal skills, with the ability to articulate complex technical concepts to non-technical stakeholders
Preferred
Experience in the biopharmaceutical or biotechnology industry
Familiarity with drug discovery, development and commercialization processes
Experience with life sciences data sources (e.g., genomic data, clinical trial data, real-world evidence, claims, specialty pharmacy/distributor)
Knowledge of GxP regulations and experience working in a regulated environment
Benefits
Discretionary annual target bonus
Stock options
ESPP
401k match
Top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance
20 days of PTO
10 paid holidays
Winter company shutdown
Company
Crinetics Pharmaceuticals
Crinetics is a clinical-stage pharmaceutical company that develops therapies for people with rare endocrine diseases.
501-1000 employees
Funding
Current Stage
Public CompanyTotal Funding
$2BKey Investors
Frazier Healthcare PartnersNational Institutes of HealthPerceptive Advisors
2026-01-06Post Ipo Equity· $349.22M
2024-10-08Post Ipo Equity· $500M
2024-02-28Post Ipo Equity· $350M
Leadership Team
R. Scott Struthers
Founder, CEO
A
Alan S. Krasner
Chief Endocrinologist
Recent News
BioWorld Financial Watch
2026-01-15
Company data provided by crunchbase