Alnylam Pharmaceuticals · 22 hours ago
Associate Scientist II, Protein Sciences
Alnylam Pharmaceuticals is a leader in RNAi therapeutics, seeking an Associate Scientist II to join their protein sciences team. The role involves contributing to protein production and conjugation efforts, working closely with cross-functional teams to deliver and validate proteins while maintaining laboratory infrastructure and records.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Responsibilities
Work closely with the protein sciences team to deliver and validate proteins and protein conjugates at various production scales
Design, plan, and perform protein conjugation experiments to support in vitro and in vivo evaluations, contributing to project-related scientific activities with some guidance from team members
Utilize UV–Vis spectroscopy and HPLC to analyze, purify, quantify, characterize, and formulate protein conjugates
Contribute to the maintenance of laboratory infrastructure and equipment
Support group organization, productivity, and expertise through collaboration and idea exchange
Meet quality, quantity, and timeline expectations for all assigned projects
Support discovery efforts in protein sciences
Maintain accurate and complete electronic notebook records
Communicate experimental plans and data to multiple cross-functional scientific teams
Qualification
Required
BS/MS degree in biology, biochemistry, biophysics, chemistry, or a related field, with 0–1 years of relevant laboratory experience in a biopharma or academic setting
Experience with modern bioconjugation chemistry and analytical techniques
Experience with instrumentation such as Agilent and ÄKTA HPLC systems, TFF, and UV–Vis spectrometry
Experience with protein and protein conjugate analysis (e.g., affinity chromatography, SEC, RP-HPLC, HIC, IEX, SDS-PAGE, UV–Vis spectroscopy) and label-free binding techniques (SPR and/or BLI)
Passion for driving projects from the bench, independently contributing to research goals, and solving challenging problems
Detail-oriented, self-motivated, and comfortable working on highly technical projects in a multidisciplinary team setting
Effective written and oral communication skills
Preferred
Experience with protein and protein conjugate analysis (e.g., affinity chromatography, SEC, RP-HPLC, HIC, IEX, SDS-PAGE, UV–Vis spectroscopy) and label-free binding techniques (SPR and/or BLI)
Experience developing new chromatographic methods
Knowledge of protein purification using ÄKTA systems
Benefits
Medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
A 401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Recent News
Clinical Trials Arena
2026-01-16
Longevity.Technology
2026-01-14
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