Ionis Pharmaceuticals, Inc. · 19 hours ago
2026 Summer Intern | Antibody Engineering
Carlsbad, CA
Internship
Hybrid
Intern
$18/hr - $23/hr
Start in 2026 SummerIonis Pharmaceuticals, Inc. is a pioneer in RNA-targeted medicines, focusing on innovative drug discovery that transforms lives. The summer intern will engage in a ligand engineering project aimed at optimizing Blood-Brain Barrier ligands for oligonucleotide delivery, utilizing protein engineering techniques and yeast surface display technology.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Perform high-throughput mutational scanning on BBB ligands to improve the delivery of oligonucleotides to the CNS
Implement and utilize yeast display platforms to present engineered variants for screening
Conjugate variants to oligonucleotides and assess conjugation efficiency
Use multi-parameter flow cytometry to evaluate expression levels, antigen-binding functionality, and conjugation success
Analyze experimental results to identify mutants with improved CNS delivery
Qualification
Required
MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship
MUST be able to begin internship between 6/8 and 8/14/2026
MUST be able and willing to remain in program through at least 8/14/2026
MUST be able and willing to commit to a minimum 40-hour work week
Benefits
Weekly stipend (for onsite interns only)
Housing/Travel assistance available for eligible, out-of-area interns
Professional Networking
End-of-program project presentations
Networking and bonding social events
Interaction with diverse and motivated teams/departments
Company
Ionis Pharmaceuticals, Inc.
For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.
Founded in 1989
501-1000 employees
H1B Sponsorship
Ionis Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (5)
2023 (3)
2022 (5)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.45B2025-11-13Post Ipo Debt· $700M
2024-09-09Post Ipo Equity· $500.3M
2023-06-06Post Ipo Debt· $500M
Leadership Team
Brett P. Monia
Chief Executive Officer
Eric Bastings
Senior Vice President, Development Strategy
Recent News
Labiotech UG
2026-01-22
Business Wire
2026-01-22
Company data provided by crunchbase