Eli Lilly and Company · 3 days ago
Engineer - Computer-Aided Engineering (DDCS)
Indianapolis, IN
Full-time
Onsite
Mid Level
$102K/yr - $172K/yr
3+ years expEli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana, dedicated to making life better for people around the world. The Engineer - Computer-Aided Engineering (DDCS) role involves developing and interpreting in silico models to support device development and collaborating with cross-functional teams to enhance modeling processes.
BiotechnologyHealth CareMedicalPharmaceutical
No H1B
Responsibilities
Develop, execute, and interpret in silico models to support device development, design optimization, and technical risk mitigation across early- and late-phase programs
Build reusable simulation frameworks, material libraries, and standardized workflows to improve efficiency and consistency
Communicate modeling assumptions, methods, and results to cross-functional stakeholders, including non-technical audiences
Author and review technical reports and regulatory submission content (IND/CTX, CTD) related to computational modeling
Define physical testing requirements in collaboration with internal teams and external partners to support model input and validation activities
Manage external vendor relationships for modeling support and component design evaluation
Evaluate emerging simulation methodologies, regulatory expectations, and industry practices; recommend and implement relevant advancements
Contribute to model governance and credibility assessment frameworks aligned with ASME V&V 40
Collaborate with cross-functional teams, including Formulation Science, Device Engineering, Quality, Regulatory, and Manufacturing
Maintain a quality mindset by identifying issues proactively and supporting continuous improvement
Qualification
Required
MS in Mechanical Engineering, Biomedical Engineering, Computational Mechanics, or related field with 3+ years of FEA experience
Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1
Expertise in commercial FEA solvers (e.g., Abaqus, ANSYS), including nonlinear analysis, contact mechanics, and material modeling (hyperelastic, viscoelastic, plasticity)
Proficiency in preprocessing tools (e.g., HyperMesh) and scripting languages (Python, MATLAB, or solver-native)
Working knowledge of ASME V&V 40 and FDA guidance on computational modeling for medical devices
Familiarity with medical device design controls (ISO 13485, 21 CFR Part 820)
Strong technical writing and verbal communication skills
Ability to manage multiple projects and deliver against timelines with minimal oversight
Effective problem-solving and decision-making capabilities
Collaborative approach in interdisciplinary team environments
Preferred
Experience with multiphysics simulation (e.g., COMSOL, Ansys Fluent)
Exposure to ML/AI applications in simulation (surrogate modeling, design space exploration)
Familiarity with model-based systems engineering, digital twin concepts, or uncertainty quantification methods
Knowledge of materials and components common to pharmaceutical delivery systems (injection-molded plastics, elastomers, glass/polymer containers, spring mechanisms)
Experience with design for manufacturing principles
Benefits
Company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
Fierce Healthcare
2026-02-07
Company data provided by crunchbase