Associate Director - Protein Engineering and Production jobs in United States
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AstraZeneca · 15 hours ago

Associate Director - Protein Engineering and Production

AstraZeneca is a biopharmaceutical company focused on delivering life-changing medicines. They are seeking an Associate Director to lead the Protein Engineering and Production team, overseeing a group of scientists and collaborating with engineering teams to optimize large-scale antibody production processes.

BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Lead, manage, and mentor a production-focused team of scientists in a high-throughput, fast-paced environment
Provide strong leadership with an emphasis on team development, scientific excellence, and delivery on production goals
Collaborate cross-functionally with automation engineers, software developers, and scientific teams to optimize and scale production processes
Oversee design and execution of protein expression and purification workflows, integrating automation to improve throughput and quality
Ensure scientific robustness in production of multispecific antibody formats, with a focus on timelines and operational efficiency
Present complex data and strategic updates to senior leadership and cross-functional stakeholders
Drive continuous improvement through workflow optimization, problem-solving, and technological innovation

Qualification

Protein productionMolecular biologyLeadership experienceAutomated liquid handlingHigh-throughput technologiesProject managementTeam developmentScientific rigorCommunication skillsProblem-solving abilitiesCollaboration

Required

PhD in Biotechnology, Molecular Biology, Biochemistry, or related field with 5+ years of post-degree experience in protein production or engineering. (Master's with 10+ years, or Bachelor's with 15+ years will also be considered.)
Proven leadership experience, preferably with direct people management and oversight of a production or operations team
Deep expertise in molecular biology, cloning, expression, and purification of therapeutic proteins
Demonstrated experience working in or with multi-disciplinary engineering teams (e.g., automation, software, bioengineering)
Hands-on experience with automated liquid handling systems (e.g., Hamilton, Lynx)
Excellent problem-solving abilities and familiarity with high-throughput technologies
Strong organizational and project management skills; proven ability to drive timelines and deliverables
Excellent communication skills; able to translate complex science into actionable plans and presentations

Preferred

Experience developing or optimizing automated workflows and using scheduling software (e.g., Green Button Go)
Familiarity with Python, Jupyter notebooks, or data analysis tools
Experience with CHO or HEK293 cell lines and tissue culture
Exposure to design of experiments (DoE) for process optimization
Background in antibody discovery, imaging, or flow cytometry (iQue, FlowJo, Attune)
Track record of scientific publications, patents, or conference presentations

Company

AstraZeneca

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AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.

H1B Sponsorship

AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (2)
2020 (11)

Funding

Current Stage
Public Company
Total Funding
$5.26B
2024-07-30Post Ipo Debt· $1.51B
2023-02-28Post Ipo Debt· $2.25B
2023-02-24Post Ipo Debt· $1.5B

Leadership Team

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Pascal Soriot
Executive Director and Chief Executive Officer
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Aradhana Sarin
Group CFO and Executive Director
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Company data provided by crunchbase