Tessera Therapeutics · 13 hours ago
Senior Research Associate, Oligonucleotide Chemistry
Somerville, Massachusetts, United States
Full-time
Onsite
Mid, Senior Level
$90K/yr - $108K/yr
5+ years expTessera Therapeutics is pioneering Gene Writing™, a new biotechnology aimed at curing diseases at their source. They are seeking a Senior Research Associate to develop and implement strategies for the enzymatic ligation and purification of oligonucleotides, while optimizing manufacturing processes in a cGMP-compliant environment.
BiopharmaBiotechnologyGeneticsLife ScienceTherapeutics
Responsibilities
Developing and implementing strategies for enzymatic ligation and purification of complex oligonucleotides
Optimizing chemical reactions and purification methods to ensure scalable and cost-effective manufacturing processes for oligonucleotides
Supporting process scale-up and transition into a cGMP-compliant manufacturing environment
Participate in cross-functional teams and training to gain familiarity in all stages of oligonucleotide research and manufacturing
Qualification
Required
BS/MS in Chemistry, Biochemistry, Chemical Engineering, or related field with 5+ years (BS) or 3+ years (MS) of relevant industry experience
Excellent knowledge and thorough understanding of upstream and downstream processing of oligonucleotides
Experience with enzymatic ligation and HPLC purification of oligonucleotides
Experience using Agilent and Waters analytical instruments for purity analysis
Detail and results oriented with experience using ELNs to document experiments and results
Preferred
Experience working in a cGMP environment
Benefits
Group medical, vision, and dental coverage
Group life and disability insurance
A 401(k) plan with company contribution
Tuition reimbursement
Annual incentive bonus
Equity grants
Company
Tessera Therapeutics
Tessera Therapeutics is a biotechnology company pioneering Gene Writing™ to drive advancements in genome engineering.
201-500 employees
H1B Sponsorship
Tessera Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (21)
2024 (52)
2023 (18)
2022 (13)
2021 (10)
Funding
Current Stage
Growth StageTotal Funding
$773.06MKey Investors
RegeneronAdvanced Research Projects Agency for HealthBill & Melinda Gates Foundation
2025-12-01Corporate Round· $150M
2025-10-08Grant· $41.3M
2024-12-18Series Unknown· $50M
Leadership Team
Michael Severino
CEO
Anne-Virginie Eggimann
Chief Regulatory Officer
Recent News
BioWorld Financial Watch
2026-01-15
2026-01-11
Company data provided by crunchbase