Centessa Pharmaceuticals · 16 hours ago
Scientist, Drug Safety (Pharmacovigilance)
Boston, MA
Full-time
Hybrid
Mid, Senior Level
$120K/yr - $157K/yr
5+ years expCentessa Pharmaceuticals plc is a new kind of pharmaceutical company with a focus on data-driven decision making. The Scientist, Drug Safety (Pharmacovigilance) will support pharmacovigilance activities, contributing to safety data analysis, regulatory compliance, and collaboration with cross-functional partners to ensure high-quality safety deliverables.
BiotechnologyPharmaceutical
Responsibilities
Conduct scientific review and evaluation of ICSRs and clinical trial SAEs, ensuring completeness, accuracy, medical consistency, and regulatory reportability
Prepare high quality case narratives and support regulatory ready ICSR submissions, including SUSARs, in accordance with global reporting requirements
Perform ongoing safety surveillance through analysis of adverse event data, identification of safety signals, and interpretation of emerging safety trends across investigational and marketed products
Conduct literature surveillance to identify and evaluate safety findings relevant to company products and development programs
Ensure the scientific integrity and quality of safety data, including performing medical and data quality review of individual case safety reports
Support preparation, review, and scientific input into safety deliverables such as DSURs, line listings, Risk–Benefit assessments, and safety-related sections of protocols, IBs, and regulatory submissions
Participate as the drug safety representative on cross-functional study teams, providing scientific expertise on safety strategy, risk assessment, and safety issue management
Maintain current knowledge of therapeutic areas and global drug safety regulations, guidelines, and industry best practices (e.g., FDA, EMA, ICH, CIOMS)
Collaborate with cross-functional partners—including clinical development, clinical operations, regulatory, medical writing, and quality—to support comprehensive safety oversight and ensure compliance
Contribute scientific expertise to ad-hoc evaluations and cross-functional safety-related projects as needed
Qualification
Required
RN or bachelor's degree in health sciences or related field required
5+ years of experience of experience in drug safety in the biotech/pharmaceutical industry with 3+ years of pharmacovigilance compliance experience
Prior experience participating in Safety Risk Assessment Meetings / Safety Review activities required
Working knowledge of global PV regulations and guidelines applicable to clinical development (e.g., FDA, EMA, ICH, GCP)
Experience with PV databases and safety surveillance tools (e.g., Argus, ArisGlobal, Vault Safety); familiarity with MedDRA coding preferred
Experience supporting clinical safety case processing and aggregate reporting
Strong analytical skills, attention to detail, and comfort working across multiple programs
Clear communicator who works effectively in small, cross-functional teams
Preferred
Advanced Degree (PharmD, PhD strongly preferred)
Experience with PV databases and safety surveillance tools (e.g., Argus, ArisGlobal, Vault Safety); familiarity with MedDRA coding preferred
CNS experience preferred
Benefits
Discretionary annual bonus
Participation in our equity program
401(k) plan
Company-sponsored medical, dental, vision, and life insurance
Generous paid time off
Health and wellness program
Company
Centessa Pharmaceuticals
Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process.
51-200 employees
H1B Sponsorship
Centessa Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.12BKey Investors
Oberland Capital
2025-11-11Post Ipo Equity· $250M
2024-09-11Post Ipo Equity· $225M
2024-04-23Post Ipo Equity· $100M
Leadership Team
John Crowley
Chief Financial Officer
Gregory Weinhoff
Chief Business Officer
Recent News
BioWorld Financial Watch
2026-01-22
2026-01-05
Company data provided by crunchbase