Prellis Biologics · 17 hours ago
Associate Scientist-Sr. Associate Scientist, Cell Based Assays
Berkeley, CA
Contract
Onsite
Mid, Senior Level
$102K/yr - $125K/yr
3+ years expPrellis Biologics is a pre-IPO biotech company located in Berkeley, CA, focused on revolutionizing drug discovery through the integration of human biology and machine learning. They are seeking a highly motivated Associate Scientist – Senior Associate Scientist for their Antibody Screening team to support antibody discovery programs by developing and executing robust cell-based binding and functional assays.
3D PrintingBiopharmaBiotechnologyTherapeutics
Responsibilities
Design, develop, optimize, and execute on-cell binding assays (e.g., flow cytometry, imaging-based, receptor internalization, competition formats) to evaluate antibody binding to native target conformations
Establish and run functional assays relevant to mechanism of action, including but not limited to: receptor signaling, internalization assays, blocking/competition assays, reporter-based pathway activation assays
Adapt assays for medium to high-throughput screening of large antibody panels, including primary screening and secondary confirmation formats
Transfer and scale assays from development to routine screening, ensuring robustness, reproducibility, and suitability for automation
Execute high-throughput antibody screening campaigns, including assay setup, sample handling, data acquisition, and preliminary analysis
Perform routine mammalian cell culture, including maintenance, expansion, cryopreservation, and quality control of multiple adherent and suspension cell lines
Maintain meticulous experimental records and effectively communicate findings in internal meetings
Qualification
Required
B.S in Biology, Chemistry, Immunology, Biotechnology, or related life science field with 5+ years of relevant experience, or M.S. with 3+ years of relevant experience in antibody discovery, cell biology, or assay development
Hands-on experience with cell-based binding assays (e.g., flow cytometry, imaging, ligand-receptor interaction assays)
Demonstrated experience developing and running functional assays for biologics (signaling, internalization, blocking, effector function, reporter assays)
Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment
Ability to work independently and as part of a collaborative team
Preferred
Familiarity with high-throughput screening environments and automated liquid handling is a plus
Company
Prellis Biologics
Prellis employs holographic tissue printing technology with fully human antibody discovery, in vitro human disease and ADME/Tox models.
11-50 employees
H1B Sponsorship
Prellis Biologics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (2)
Funding
Current Stage
Growth StageTotal Funding
$79.37MKey Investors
Celesta CapitalKhosla VenturesTrue Ventures
2025-03-10Series C
2023-11-17Series C
2022-08-10Series C· $35M
Leadership Team
Michael Nohaile
Chief Executive Officer
Recent News
Corridor Business Journal
2025-11-26
Company data provided by crunchbase