Pfizer · 18 hours ago
Senior Associate Scientist- In Vivo Pharmacologist
United States - Massachusetts - Cambridge
Full-time
Onsite
Mid, Senior Level
$69K/yr - $111K/yr
3+ years expPfizer is a leading biopharmaceutical company dedicated to delivering breakthroughs that transform patients' lives. They are seeking a highly motivated Senior Associate Scientist to support the expansion and optimization of in vivo pharmacology platforms, focusing on humanized systems and evaluating the efficacy of novel therapeutics.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
No H1B
Responsibilities
Expand critical capabilities by designing and executing comprehensive in vivo model-development studies
Support the portfolio by planning and conducting pharmacology studies to evaluate mechanisms of action and therapeutic efficacy for pipeline molecules
Perform specialized research using human cell-engrafted immunocompromised mice, including aseptic execution of cell preparation and in vivo techniques
Profile models and drug performance through tissue collection and ex vivo assays, including flow cytometry and multiplex immunoassays
Generate high quality data packages with well documented methods, analyses, and interpretations for project team presentations
Enhance operational efficiency and scientific impact by collaborating with partner line colleagues, including modelers and statisticians, and across in vivo teams, including neuro- and lung- inflammation-focused groups
Qualification
Required
A Bachelor's Degree with ≥3 years of relevant experience or a Master's Degree with ≥1 year of relevant experience
Foundational knowledge of immunology, autoimmunity, and pharmacology
Experience in in vivo preclinical research, ideally in a biotech or pharmaceutical environment
Proficiency with in vivo techniques, including intraperitoneal, oral, and intravenous dosing; submandibular bleeds; aseptic handling of immunocompromised mice; and tissue collection
Hands-on experience with tissue processing for and execution of molecular biology techniques, including flow cytometry, multiplex immunoassays, and RT-PCR
Proficiency with data analysis and documentation tools like Excel, GraphPad Prism, FlowJo, PowerPoint, and Signals Electronic Lab Notebook
Strong time-management skills with the ability to follow established protocols, develop new methods and troubleshoot independently
Excellent written and verbal communication skills; strong organizational skills; and attention to detail
Ability to work independently as well as collaboratively within multidisciplinary teams
Preferred
Experience with cell culture and human primary cell handling
Familiarity with animal models of neuroinflammation and/or lung inflammation, including relevant techniques such as intracerebroventricular injection/implantation and/or intratracheal dosing
Skills in tissue sectioning, histology, and immunostaining
Benefits
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Company
Pfizer
Pfizer is a biopharmaceutical company that discovers, develops, and delivers medicines and vaccines.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$38BKey Investors
Starboard Value
2025-11-21Post Ipo Debt· $6B
2024-10-07Post Ipo Equity· $1B
2023-05-16Post Ipo Debt· $31B
Leadership Team
Albert Bourla
Chief Executive Officer
Ian Read
Chief Executive Officer
Recent News
2026-01-25
Pharma Letter
2026-01-25
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