AbbVie · 16 hours ago
Principal Research Scientist I, siRNA Therapeutics
South San Francisco, CA
Full-time
Onsite
Senior Level, Lead/Staff
6+ years expAbbVie is a company dedicated to discovering and delivering innovative medicines and solutions for serious health issues. They are seeking a highly motivated and collaborative scientist with a background in therapeutic siRNA to advance their siRNA pipeline for oncology indications, directing research and mentoring other scientists in the process.
BiotechnologyFinancial ServicesHealth CareMedicalPharmaceuticalVenture Capital
Responsibilities
Function as a principal investigator to advance internal siRNA technology and programs related to oncology indications
Independent responsibility for project science within his/her area of expertise on one or more project teams
Collaborate with therapeutic area colleagues to advance siRNA technology applied to internal programs. Direct research and mentor a group of scientists within area of expertise
Optimize internal siRNA platforms for targeted functional delivery of siRNA
Manage external CROs and internal resources to meet budget and timeline constraints
Collaborate closely with internal colleagues to advance cross-functional collaborative experiments and projects
Serve as a subject matter expert for siRNA delivery to target tissues and experimental design & execution
Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific advanced or competitive threats and respond with appropriate new strategies
Clearly communicate technology achievements and needs with management and cross functional collaborators
Qualification
Required
BS, MS, or PhD with typically 14+ years (BS), 12+ years (MS), or 6+ years (PhD) of related work experience in biotech or pharma
Previous experience with therapeutic siRNA, siRNA antibody conjugates, and downstream assays to measure efficacy is required
Previous experience managing and leading direct report scientists
Deep experience in cell culture techniques and downstream assays to evaluate RNAi compounds
Previous experience in animal study design and downstream assays to evaluate genetic medicines
Excellent communication and interpersonal skills. Listens and understands others' point of view and articulates own perspective tacitly in order to clearly communicate scientific findings with key stakeholders
Preferred
Experience with extrahepatic delivery of therapeutic siRNA is a plus
Candidate will be well versed in the field of oncology with previous experience preferred
Benefits
Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Short-term incentive programs
Long-term incentive program
Company
AbbVie
AbbVie is a biopharmaceutical company focused on immunology, oncology, neuroscience, virology, and aesthetics. It is a sub-organization of AbbVie.
10001+ employees
H1B Sponsorship
AbbVie has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (273)
2024 (190)
2023 (225)
2022 (284)
2021 (186)
2020 (186)
Funding
Current Stage
Public CompanyTotal Funding
$15B2024-02-27Post Ipo Debt· $15B
2023-03-08Post Ipo Equity· $0.25M
2012-12-20IPO
Leadership Team
Robert Michael
Chairman of the Board and Chief Executive Officer
Micah Bregman
Vice President, Global Strategy and Pipeline, Allergan Aesthetics
Recent News
2026-01-23
2026-01-20
2026-01-20
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