Acrivon Therapeutics, Inc. · 8 hours ago
Senior Clinical Trial Manager
Watertown, MA
Full-time
Onsite
Senior Level
5+ years expAcrivon Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on developing precision medicines. The Senior Clinical Trial Manager will oversee a Phase I/II clinical trial, ensuring milestones are met while managing relationships with sites and vendors to maintain regulatory compliance and deliver timely results.
BiotechnologyHealth CareOncologyTherapeutics
Responsibilities
Oversees site initiation, subject enrollment, clinical monitoring, compliance at clinical sites, and metrics management with CROs, central labs, and external vendors
Ensures high-quality execution throughout clinical trial initiation, conduct, and closure
Manages study budgets, contracts with vendors, and negotiates agreements to track and control costs effectively
Guides cross-functional teams in achieving study timelines, strategies, goals, and quality benchmarks
Evaluates and ensures effective oversight of Contract Research Organizations (CROs) and other vendors, fostering strong partnerships
Communicates effectively with clinical trial sites to maintain project momentum
Updates stakeholders on trial progress to align expectations, priorities, and deliverables
Contributes to study-level budget development and takes responsibility for budget management
Identifies and addresses risks associated with clinical studies and investigator sites, implementing corrective actions as needed
Leads operational activities detailed in study plans, SOPs, and other study-related documents
Reviews critical study documents, including protocols, informed consent forms, and operational materials
Assesses monitoring visit reports to verify site training adequacy and resolve any outstanding issues promptly
Qualification
Required
Minimum of a bachelor's degree in a scientific or health-related discipline
Minimum of 5+ years of Clinical Operations and Clinical Trial Management experience at a contract research organization, biotech or pharmaceutical company preferably in early to mid-phase oncology
Proven leadership skills managing cross-functionally in a matrix environment
Demonstrated ability to build strong relationships with external partners, CROs, and vendors including extensive experience managing contracts and clinical finance activities
Strong verbal and written communication skills with ability to communicate and work productively in a team environment
Proficient computer skills i.e. Microsoft Project, Word, PowerPoint, and Excel
Proven ability to multi-task and work collaboratively as well as independently
Ability to organize and manage multiple priorities required
Company
Acrivon Therapeutics, Inc.
Acrivon Therapeutics is a precision oncology therapeutics company uniquely enabled by a differentiated proteomics-based patient selection platform.
11-50 employees
H1B Sponsorship
Acrivon Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
Funding
Current Stage
Public CompanyTotal Funding
$245.5M2024-04-09Post Ipo Equity· $130M
2022-11-15IPO
2021-11-11Series B· $100M
Leadership Team
Eric Devroe
Chief Operating Officer
Recent News
2026-01-09
2026-01-09
Company data provided by crunchbase