Parabilis Medicines · 12 hours ago
Principal Architect, Cloud Solutions
Cambridge, MA
Full-time
Onsite
Lead/Staff
$160K/yr - $200K/yr
8+ years expParabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines. They are seeking a Principal Architect, Cloud Solutions to define and advance their cloud, AI, and data infrastructure strategy, while owning the design of secure, scalable AWS environments that support AI development and enterprise workloads.
Biotechnology
Responsibilities
Define and execute the company's cloud and AI platform architecture and multi-year roadmap
Design and implement secure, scalable AWS solutions supporting research, clinical, and business operations
Architect cloud infrastructure for AI/ML workloads, including model training, deployment, and reproducibility
Establish and maintain AWS landing zones, account structures, networking, and identity foundations
Lead Infrastructure as Code, CI/CD automation, and cloud-native deployment practices
Embed security, compliance, and data integrity principles (GxP, HIPAA, GDPR, SOX) into all designs
Implement monitoring, observability, cost management, and high-availability/disaster recovery patterns
Partner across IT, Data Science, and business teams to translate needs into durable technical solutions
Mentor engineers and data scientists on cloud-native and AI-enabling best practices
Serve as the principal cloud architecture advisor for stakeholders across the organization
Qualification
Required
8-10+ years designing and operating cloud infrastructure, including 7+ years of deep AWS experience
Proven success architecting secure, scalable, highly available platforms in regulated or research-driven environments
Strong hands-on expertise with Infrastructure as Code, CI/CD pipelines, and automation frameworks
Experience supporting AI/ML workloads, including LLM-based applications
Deep knowledge of AWS networking, IAM, security architecture, and hybrid connectivity
Demonstrated experience embedding compliance frameworks (GxP/FDA, HIPAA, GDPR, SOX) into cloud systems
Proficiency in Python or similar scripting languages for automation and integration
Ability to translate complex scientific and business requirements into robust architectures
Strong communication skills with the ability to influence without formal authority
Active, practical use of AI tools in current or recent roles (advanced or innovative use is a plus)
Benefits
Annual target bonus
Equity
A comprehensive suite of competitive benefits designed to support our employees' overall well-being
Company
Parabilis Medicines
Parabilis Medicines™ is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for people living with cancer.
51-200 employees
H1B Sponsorship
Parabilis Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (4)
2023 (1)
2022 (2)
2020 (2)
Funding
Current Stage
Growth StageLeadership Team
Mathai Mammen, M.D., Ph.D.
Chairman, CEO and President
Weiqing Zhou
Co-founder & COO
Recent News
Google Patent
2025-05-04
Google Patent
2025-05-04
Company data provided by crunchbase