Atavistik Bio · 7 hours ago
Principal Scientist, Biology
Cambridge, MA
Full-time
Onsite
Senior Level, Lead/Staff
$145K/yr - $160K/yr
5+ years expAtavistik Bio is a privately-held clinical stage biotechnology company focused on developing precision allosteric therapeutics. They are seeking a Principal Scientist with expertise in hematologic malignancies to lead the biology and translational research strategy for small molecule drug candidates, collaborating with various partners and communicating findings to stakeholders.
BiotechnologyHealth CareLife ScienceTherapeutics
Responsibilities
Work closely with broader drug discovery scientific team to progress compounds from screening to preclinical animal models
Work with CRO and academic partners on a wide-range of drug discovery efforts including cell-based screening and primary patient cell-based assays
Partner with CROs and academic partners to design and execute in vivo PK/PD and efficacy models
Develops and executes the translational science strategy in collaboration with the Clinical Development organization
Designs and implements translational research plans to identify and validate biomarkers for patient selection strategy, treatment response, and disease progression
Clearly communicates the biology, translational research strategy, data, and other information to employees, company leadership, and external stakeholders including key opinion leaders, board members, and investors
Supports the preparation of regulatory documents, including IND submissions, clinical study protocols, and reports
Drafts and submits data for scientific publications and presents our research and development programs at scientific conference and to regulatory agencies
Qualification
Required
PhD. in Biology with 5+ years of experience in industry, with a strong focus on drug discovery in hematologic malignancies
Strong interpersonal skills and ability to build strong collaborative relationships in a cross-functional environment is a must
Deep knowledge of preclinical in vivo models of hematologic malignancies, in particular myeloproliferative neoplasms
Ability to think strategically with consideration of translational proof of concept, competitive landscape, and optimal patient populations
Strong oral and written communication skills, with experience presenting complex scientific data to both internal and external stakeholders, including regulatory agencies
Benefits
Competitive compensation
Equity-based compensation
Comprehensive benefits package
Medical
Dental
Vision
401(k) retirement plan
Life insurance
Flexible spending account for either health care and/or dependent care
Company
Atavistik Bio
Atavistik Bio is a biotechnology company that develops precision allosteric small molecules aimed at treating metabolic diseases and cancer.
11-50 employees
H1B Sponsorship
Atavistik Bio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
2022 (2)
Funding
Current Stage
Growth StageTotal Funding
$220MKey Investors
The Column Group
2025-12-18Series B· $120M
2023-12-19Series Unknown· $40M
2021-08-24Series A· $60M
Leadership Team
Bryan Stuart
Chief Executive Officer
John A. Josey
Acting Chief Executive Officer
Recent News
2025-12-20
2025-12-19
Company data provided by crunchbase