Ionis Pharmaceuticals, Inc. · 2 hours ago
Accounts Payable Senior Manager
Carlsbad, CA
Full-time
Hybrid
Senior Level, Lead/Staff
$81K/yr - $115K/yr
8+ years expIonis Pharmaceuticals, Inc. is a pioneer in RNA-targeted medicines, dedicated to discovering medical breakthroughs for serious diseases. The Accounts Payable Senior Manager will oversee day-to-day Accounts Payable and Travel & Expense operations, ensuring timely and compliant processing, while also leading the AP team and managing operational challenges.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Oversee daily Accounts Payable operations to ensure timely invoice processing and payments
Oversee daily Concur operations to ensure timely expense report audit and approvals
Monitor workload, invoice and expense aging, and operational metrics to meet monthly close and service-level objectives
Ensure compliance with internal controls, policies, and audit requirements
Assist with internal Audit requirements to incorporate formal audit on the T&E side
Act as the primary operational escalation point for AP and T&E issues
Oversee AP and T&E shared mailboxes to ensure timely and professional responses
Partner with cross-functional teams to resolve operational issues impacting AP and T&E
Manage, coach, and develop AP team members, including workload assignment and prioritization
Conduct regular one-on-ones, provide performance feedback, and complete year-end performance reviews
Ensure consistent execution of processes and accountability across the team
Lead the operational execution of system upgrades and enhancements (SAP, Coupa, Concur) with guidance and oversight from the AP Associate Director
Ensure users are prepared for system changes, issues are resolved timely, and post-go-live operations are stabilized
Maintain operational documentation and ensure adherence to established procedures
Support internal and external audits by preparing documentation and responding to audit requests
Support month-end close activities, including accruals, reconciliations, and variance analysis
Lead the Form 1099 preparation and review
Qualification
Required
Associate's degree in Accounting, Finance, or related field (or equivalent experience)
8–10+ years of Accounts Payable experience, including people management
Strong knowledge of AP and T&E operations, payments, reconciliations, and month-end close
Hands-on experience with ERP and AP systems (SAP preferred; Coupa and Concur)
Strong leadership, problem-solving, organizational, and communication skills
Ability to operate independently, manage ambiguity, and prioritize competing operational demands
Benefits
Ionis offers an excellent benefits package!
Company
Ionis Pharmaceuticals, Inc.
For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.
501-1000 employees
Funding
Current Stage
Public CompanyTotal Funding
$2.45B2025-11-13Post Ipo Debt· $700M
2024-09-09Post Ipo Equity· $500.3M
2023-06-06Post Ipo Debt· $500M
Leadership Team
Brett P. Monia
Chief Executive Officer
Eric Bastings
Senior Vice President, Development Strategy
Recent News
Labiotech UG
2026-01-22
Business Wire
2026-01-22
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