Principal Enterprise Architect, Digital Solutions jobs in United States
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McKesson · 2 hours ago

Principal Enterprise Architect, Digital Solutions

positionIrving, TX
timeFull-time
remoteOnsite
seniorityLead/Staff
money$179K/yr - $298K/yr
date13+ years exp

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. The Principal Enterprise Architect, Digital Solutions is responsible for defining and advancing the enterprise digital architecture strategy to enable scalable, secure, and innovative digital solutions for US Oncology Practices.

BiopharmaBiotechnologyHealth CareInformation TechnologyPharmaceutical
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H1B Sponsor Likelynote

Responsibilities

Define and evolve the enterprise digital architecture vision, principles, and roadmaps aligned with business objectives
Provide architectural leadership for major digital initiatives, platform strategies, and transformation programs
Advise executives and senior leaders on technology trends, risks, and long-term architectural implications
Ensure digital solutions are secure, scalable, interoperable, and compliant with enterprise and regulatory standards
Establish and maintain reference architectures, patterns, and governance
Influence and mentor architects and technical leaders through thought leadership

Qualification

Enterprise architectureCloud modernizationIntegration architectureData platformsAI/ML applicationTOGAF certificationAWS/Azure Architect certificationOncology experienceClinical operations experienceSoft skills

Required

Degree or equivalent and typically requires 13+ years, with 8+ years, of direct work-related experience. Less years required if has relevant Master's or Doctorate qualifications
Extensive experience in enterprise architecture or engineering leadership roles
Expertise in cloud modernization, multi-tenant platforms, and large-scale system design
Strong integration architecture background with APIs and interoperability standards
Experience with data platforms, semantic layers, analytics, and governed access models
Familiarity with clinical systems and oncology digital workflows preferred

Preferred

Experience in oncology, clinical operations, or life sciences
Certifications: TOGAF, AWS/Azure Architect
Experience applying AI/ML to enterprise digital solutions, defining AI platform standards, and familiarity with cloud‑native AI services

Benefits

Competitive compensation package
Annual bonus
Long-term incentive opportunities

Company

McKesson

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McKesson distributes medical supplies, information technology, and care management products and services.
dateFounded in 1833
location
Irving, Texas, USA
people-size10001+ employees
web-link
http://www.mckesson.com

H1B Sponsorship

McKesson has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (149)
2024 (129)
2023 (82)
2022 (142)
2021 (144)
2020 (154)

Funding

Current Stage
Public Company
Total Funding
unknown
1994-11-18IPO

Leadership Team

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Brian Tyler
CEO
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Jim McAuliffe
CFO
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Recent News

PR Newswire
Coating Place Announces Leadership Appointments to Support Next Phase of Growth
2026-01-23
Business Wire
McKesson’s Practice Insights Designated as a 2026 Qualified Clinical Data Registry by Centers for Medicare & Medicaid Services
2026-01-20
GlobeNewswire
AOP Health’s Rapiblyk™ Now Accessible via Leading US Healthcare Improvement Companies
2026-01-12
Company data provided by crunchbase