Dendreon · 9 hours ago
Senior Director/Vice President, Site Operations
Seal Beach, CA
Full-time
Onsite
Director/Executive
7+ years expDendreon is transforming the battle against cancer with personalized immunotherapy and is seeking a Senior Director or Vice President of Site Operations to lead PROVENGE manufacturing. This strategic role involves overseeing U.S. site operations to align with product objectives, ensuring compliance with quality standards, and driving continuous improvement across manufacturing processes.
BiotechnologyLife ScienceTherapeutics
Responsibilities
Ensures the relevant business processes, procedures, and resources are in place to compliantly, safely and effectively produce PROVENGE and other biotech products
Represents technical operations at the Steering Committee level when interfacing with external clients
Manages technical operations at Dendreon’s commercial IMFs (Seal Beach / Union City) and contract manufacturing facilities (CMFs), as appropriate
Leads site EHS&S teams at each Dendreon facility to maintain Dendreon safety standards and align with corporate EHS&S programs
Works collaboratively with cross-functional departments to ensure strict compliance with cGMP guidelines, understanding phase-appropriate requirements for clinical and commercial manufacturing
Interfaces with external customers and FDA during audits and inspections
Develops and achieves both enterprise-wide and site performance goals
Leads metric reviews (manufacturing, safety, engineering, quality, materials, etc) across cross-functional site teams on a regular basis
Manages review and adherence to department and site budgets, including COGS
Leads and facilitates the planning and execution of a broad range of technical programs and projects as assigned (e.g. Corporate EHS&S, PMO, corporate initiatives, etc)
Provides leadership that enhances Dendreon’s culture
Able to coach, develop and retain talent across all levels
Proactively builds cross functional relationships – Apheresis Operations, Technical Operations, Supply Chain, Research and Manufacturing Sciences, Regulatory, etc
Other duties as assigned
Qualification
Required
Bachelor's degree in Life Sciences, Engineering, or a related field required; an advanced degree (MS, MBA, or PhD) is strongly preferred
At least 7-10 years in leadership roles, managing cross-functional teams and multi-site operations
Proven experience leading large-scale operational initiatives, managing complex technical programs, and guiding senior-level teams in a regulated environment
Demonstrated success in meeting and sustaining operational metrics, implementing performance improvements, and managing cost of goods (COGS) or department/site budgets
Strong business acumen, with the ability to apply business analytics and strategic insights to prioritize, influence, and make data-driven decisions
Working knowledge of cGMPs, aseptic processing, quality systems, and EHS&S regulations (OSHA, EPA), with the ability to evaluate and implement new technologies within the regulatory landscape
Skilled in inspirational leadership, strategic planning, team development, change management, and collaborative problem-solving
Excellent communication, facilitation, and presentation skills; comfortable engaging with senior executives, regulators, and cross-functional stakeholders
Ability to thrive in dynamic, fast-paced environments and effectively navigate ambiguity and abstract concepts
10–15 years of progressive experience in the pharmaceutical, biotech, or life sciences industry, with a strong background in cGMP-compliant manufacturing environments
Preferred
An advanced degree (MS, MBA, or PhD) is strongly preferred
Experience supporting regulatory inspections and audits (e.g., FDA, EMA) and working with external manufacturing partners (CMOs/CDMOs) is highly desirable
Company
Dendreon
Dendreon was a biotechnology company produces immunotherapy for prostate cancer.
501-1000 employees
H1B Sponsorship
Dendreon has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (1)
2021 (1)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
unknown2017-06-29Acquired
2000-06-23IPO
Leadership Team
Bev Eckert
Sr. Assistant to the VP& CIO
Jonathan Wells, SHRM-SCP, SPHR
Human Resources Business Partner
Recent News
MarketsandMarkets Research Pvt. Ltd.
2025-08-13
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