Upstream Bio · 16 hours ago
Senior Manager, Supply Chain Logistics
Waltham, MA
Full-time
Onsite
Senior Level, Lead/Staff
$157K/yr - $192K/yr
8+ years expUpstream Bio is a public company based in Waltham, MA, focused on developing innovative therapies for severe asthma and chronic rhinosinusitis. They are seeking a Senior Manager, Supply Chain Logistics to oversee global product movement and ensure compliance with regulatory requirements while collaborating with internal teams and external partners.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Coordinate the transportation, including import/export, of biological materials to ensure timely delivery and compliance with regulatory requirements including all customs related document generation and trade compliance activities
Facilitate communication and collaboration with internal teams and external stakeholders to ensure smooth execution of shipment related activities
Track shipments and temperature data ensuring adherence to proper storage condition, timelines and quality standards
Lead investigations into logistics excursions and proactively address OOS incidents, trend data and propose corrective actions
Author and/or collaborate with external supply partners to maintain documents to ensure effective product handling and packaging, including SOP’s, shipping and receiving forms, visual work instructions, and information sheets in accordance with GDP
Serve as the relationship manager for couriers, customs brokers and freight forwarders, and GMP storage facilities to handle all global logistics activities
Collaborate with couriers, brokers, and freight forwarders worldwide to set up and maintain shipping lanes and pricing for all products/configurations
Support the execution of shipping validation studies to enable compliant global movement of GxP materials (master and working cell banks, drug substance, drug product, final SKU (vials, PFS, autoinjectors, etc.)
Manage materials inventory, storage, capacities, and status
Maintain audit-ready documentation for all shipment related activities and ensure compliance with cGMPs and relevant FDA/EU regulations
Travel to partner sites to oversee critical activities (~5% of the time)
Qualification
Required
BS degree in Logistics, Supply Chain or related discipline with 8+ years of experience in the Biotechnology/Pharmaceutical industry
Demonstrate experience in international pharmaceutical product distribution and global clinical supply management
Proven experience in complex temperature-controlled shipping modalities (-80C, 2-8C, etc.)
Strong understanding of international logistics, harmonized tariff codes, Export Administration Regulations (EAR) and related custom regulations and documentation requirements
Strong understanding of cGMP, GDP, and GCP
Solid understanding of biotech/pharmaceutical product inventory and lot control requirements and methodologies
Exceptional attention to detail and collaborating closely with internal/external cross-functional team
Proficient knowledge of Veeva, SharePoint, Smartsheet, eTMF and IRT systems, MS Office (Excel, etc.)
Benefits
Health care
Vision
Dental
Retirement
PTO
Company
Upstream Bio
Upstream Bio focuses on developing an antibody therapy for the treatment of severe asthma. It is a sub-organization of Upstream Bio.
51-200 employees
Funding
Current Stage
Public CompanyTotal Funding
$408MKey Investors
HBM Partners
2024-10-11IPO
2023-06-08Series B· $200M
2023-02-10Series A· $8M
Leadership Team
Rand Sutherland
Chief Executive Officer
Michael Gray
Chief Financial and Chief Operating Officer
Recent News
2025-11-25
2025-11-07
2025-11-06
Company data provided by crunchbase