Avalere Health · 4 hours ago
Director, Advisory Biostatistics
United States
Full-time
Hybrid
Lead/Staff, Director/Executive
$150K/yr - $200K/yr
5+ years expAvalere Health is dedicated to ensuring every patient is identified, treated, and cared for. They are seeking a Director-level biostatistics leader to provide methodological leadership in privacy-preserving evidence generation and complex modeling across RWE/HEOR engagements.
Brand MarketingConsultingMedical
Responsibilities
Client delivery & methodological leadership (target ~40% billable)
Serve as an advanced analytics project architect for practice (Evidence & Strategy, Policy, and Market Access) engagements requiring biostatistics and complex methodology
Lead cross-practice review for power/sample size calculations, statistical design choices, and sensitivity analysis planning for high-stakes studies
Provide senior technical leadership on study design and analysis execution, including protocol development, SAP authorship/review, statistical modeling, interpretation, and defensible write-up for client and publication audiences
Act as an internal challenger to pressure-test assumptions, scopes, and deliverables, improving rigor, feasibility, and credibility before work is finalized
Architect validation and QC approaches for complex analytic tools (e.g., large Excel models or web-based analytic applications), including testing strategy, versioning expectations, and controlled change processes
Privacy certification, anonymization, and governance leadership
Lead Avalere’s approach to privacy certification/anonymization in analytics workflows, including documentation expectations and quality controls
Develop and maintain statistical QC frameworks aligned to privacy-preserving use of sensitive healthcare data
Provide practical guidance on de-identification strategies (e.g., Safe Harbor vs Expert Determination) and analytics design choices that reduce re-identification risk and improve defensibility
Business development, feasibility, and proposal support (target ~20%)
Manage and triage incoming data/analytics requests; advise on conceptual feasibility, data readiness, methodological fit, timelines, and resourcing
Lead or support a cross-practice feasibility review forum to standardize intake, solutioning, and risk/assumption documentation
Review and approve methodological sections of proposals and SOWs, including analytics scope, endpoints, data language, QC expectations, and deliverable feasibility
Standards, SOPs, and reusable IP (target ~30%)
Develop and maintain SAP templates, QC SOPs, peer review checklists, and analysis standards to improve consistency and reduce publication risk across teams
Establish documentation standards for reproducible research and auditability (e.g., protocol/SAP structure, table shells, QC logs, data dictionaries, lineage, and analysis traceability)
Serve as a methodological evaluator/challenger for in-flight tools and methodologies, recommending improvements to drive scalability, efficiency, and quality
Mentorship, enablement, and cross-functional partnership
Mentor analysts and managers; elevate statistical storytelling, defensible methods, and QC discipline across project teams
Partner with data engineering and AI/technology collaborators on evaluation design for analytics tools and accelerators (focus on fit-for-purpose use, validity, and controlled deployment rather than model-building ownership)
Qualification
Required
PhD or MS in Biostatistics, Statistics, Epidemiology, or a related quantitative field (PhD preferred)
Significant experience (typically 5+ years) applying biostatistics in US healthcare/RWE settings, including consulting or client-service delivery
Demonstrated ability to produce and/or oversee publication-grade analytics outputs, including rigorous study design, reproducibility, QC, and clear interpretation for non-technical stakeholders
Experience leading or materially contributing to privacy/anonymization approaches and associated governance/documentation for healthcare data analytics
Proven success reviewing and shaping analytical scopes for proposals/SOWs and improving feasibility, risk management, and delivery quality across teams
Advanced proficiency in R and/or Python, plus strong SQL (SAS familiarity a plus)
Depth in methods commonly required for RWE/HEOR, such as: GLM/GLMM, survival/time-to-event, longitudinal/mixed models
Causal inference approaches (e.g., propensity methods) and quasi-experimental designs
Missing data strategies and sensitivity analyses
Power/sample size and study feasibility planning
Ability to architect validation and QC for complex analytic tools (Excel/web), including testing strategy and controlled change management
Strong consulting judgment and stakeholder management; ability to translate technical conclusions into decision-ready narratives
Comfortable operating as a cross-practice reviewer and standard-setter, constructively challenging assumptions and raising the bar on rigor
Benefits
401K plan with an employer match contribution up to 4% (immediately vested)
Life insurance
Disability coverage
Medical, dental, and vision plans
Flexible working arrangements
20 vacation days plus one personal well-being day
9 public holidays
Gifted end-of-year holidays
Early Summer Friday finish in June, July, and August
Free counselling through our employee assistance program
Personalized health support
Enhanced maternity, paternity, family leave, and fertility policies
Continuous opportunities to professionally develop with on-demand training, support, and global mobility opportunities
Company
Avalere Health
Avalere Health offers business consulting, medical engagement and communications services.
1001-5000 employees
H1B Sponsorship
Avalere Health has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (5)
2024 (3)
2022 (6)
2021 (3)
2020 (1)
Funding
Current Stage
Late StageLeadership Team
Amar Urhekar
Chief Executive Officer
Corrina Safeio
President Global Marketing, EVP Corporate Marketing
Recent News
2025-12-04
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