Kymera Therapeutics · 1 day ago
Desktop Engineer
Greater Boston
Full-time
Hybrid
Senior Level
$115K/yr - $200K/yr
5+ years expKymera Therapeutics is a clinical-stage biotechnology company pioneering targeted protein degradation to develop innovative medicines. They are seeking a highly capable Desktop Engineer to serve as the L3 escalation point for endpoint and user support, ensuring a secure and reliable computing experience for employees across the organization.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Package, deploy, and maintain Win32 applications through Microsoft Intune
Build and update remediation scripts, configuration profiles, and compliance policies
Troubleshoot Autopilot enrollments, ESP issues, and device identity inconsistencies
Ensure consistent device hygiene, lifecycle management, and operational readiness
Troubleshoot hybrid identity issues involving Entra ID, Azure AD Connect, and device join states
Support user and device identity lifecycle processes
Resolve authentication failures, directory sync issues, and group-based access concerns
Contribute to identity-related troubleshooting improvements and best practices
Provide advanced troubleshooting for Exchange Online, Teams, SharePoint, and OneDrive
Diagnose and resolve mail flow problems, permission conflicts, and policy inconsistencies
Support configuration and lifecycle management of M365 Groups
Assist with cross-service issues affecting collaboration and user productivity
Diagnose OS, driver, performance, profile, and Windows Update issues using advanced tools
Analyze event logs and system telemetry to determine root causes
Identify recurring endpoint issues and recommend corrective actions
Support imaging and Autopilot health by addressing underlying system issues
Develop and maintain PowerShell scripts for support, remediation, and automation
Use JSON and basic Graph API calls when necessary
Identify opportunities to reduce manual work and improve consistency
Apply endpoint hardening practices and configuration standards
Perform initial triage of endpoint security alerts before escalation
Work closely with the Cybersecurity team on incident workflows and risk mitigation
Maintain device and user compliance with organizational policies
Troubleshoot DNS, VPN clients, Wi-Fi issues, and routing-related symptoms
Determine whether issues originate from the endpoint or the broader network
Assist users with connectivity problems affecting productivity
Use OEM diagnostic tools to identify potential hardware faults
Distinguish hardware failures from software or configuration issues
Coordinate RMAs, warranty service requests, and device replacements
Validate device health and readiness following repair or replacement
Act as an escalation point for L1 and L2 support teams
Document troubleshooting procedures, runbooks, and best practices
Collaborate with Infrastructure, Cybersecurity, and Applications teams
Contribute to continuous improvement of endpoint-related processes
Qualification
Required
5+ years supporting Windows endpoints in an enterprise environment
Experience with Microsoft Intune app deployment, policy management, and device troubleshooting
Strong troubleshooting skills across OS, identity, and Microsoft 365 services
PowerShell scripting skills for automation and remediation workflows
Solid understanding of hybrid Entra ID / Azure AD identity concepts
Experience diagnosing hardware issues and coordinating warranty repairs
Familiarity with DNS, VPN, and Wi-Fi troubleshooting
Strong written and verbal communication skills
Preferred
Experience with Defender for Endpoint
Background in hybrid AD DS + Entra ID environments
Exposure to regulated industry environments (biotech, pharma, etc.)
Experience supporting modern endpoint and collaboration ecosystems
Benefits
Eligibility for annual bonus
Equity participation
Comprehensive benefits
Company
Kymera Therapeutics
Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.
51-200 employees
H1B Sponsorship
Kymera Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (2)
2023 (4)
2022 (3)
2021 (3)
Funding
Current Stage
Public CompanyTotal Funding
$1.96BKey Investors
Biotechnology Value FundAtlas Venture
2025-12-10Post Ipo Equity· $602M
2025-06-26Post Ipo Equity· $250.8M
2024-08-19Post Ipo Equity· $225M
Leadership Team
Nello Mainolfi
Founder, President and Chief Executive Officer
Jeremy Chadwick
Chief Operating Officer
Recent News
2026-01-16
2026-01-11
Company data provided by crunchbase