Vaxcyte · 6 hours ago
Senior Associate Scientist (contract), Research
San Carlos, California, United States
Contract
Onsite
Senior Level
$56/hr - $62/hr
5+ years expVaxcyte is a clinical-stage vaccine innovation company focused on engineering high-fidelity vaccines to combat bacterial diseases. The Senior Associate Scientist will execute various chromatography techniques and design processes to purify vaccine antigens, while collaborating within a team to support research initiatives.
BiopharmaBiotechnologyHealth Care
Responsibilities
Execute the following AKTA FPLC chromatography techniques:
Immobilized metal affinity chromatography (IMAC)
Ion-exchange chromatography (IEX)
Hydrophobic interaction chromatography (HIC)
Size-exclusion chromatography (SEC)
Hydroxyapatite (CHT / HA)
Designing chromatography trains to reduce host cell protein, endotoxin and aggregates using complementary modalities
Demonstrated DoE experience for multimodal optimization is a plus
Membrane chromatography for high-throughput contaminant removal or virus/VLP processing and as a scale-friendly polishing/scavenging step
Keep accurate and current records of development experiments and/or project related activities in an electronic laboratory notebook
Present data from experiments to the team and contribute to technical discussions
Work within a team environment and provides support as necessary to further the team’s initiatives
Qualification
Required
BS in Biochemistry, Molecular Biology or a relevant science considered, with minimum of 5 years of relevant industry experience or MS with minimum of 3 years relevant industry experience
Experience with diverse protein targets, bacterial and eukaryotic recombinant proteins, small/large subunit vaccine antigens, fusion proteins, multimeric complexes, glycoproteins, and VLPs
The role requires demonstrated success with alternative capture/polishing methods and orthogonal cleaning strategies appropriate for potential vaccine antigens
Strong interpersonal skills to collaborate well within the team and excellent written and verbal communication skills
Preferred
Preferred experience with Cell-free protein synthesis system
Familiarity with automation or high throughput workflows such as (96-well plates) and UNICORN/AKTA software DoE integrations
Experience in process development
Demonstrated DoE experience for multimodal optimization is a plus
Company
Vaxcyte
Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.
201-500 employees
H1B Sponsorship
Vaxcyte has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (7)
2023 (5)
2022 (7)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$3.85BKey Investors
CARB-XTPG GrowthAbingworth
2024-09-04Post Ipo Equity· $1.5B
2024-01-30Post Ipo Equity· $862.5M
2023-04-19Post Ipo Equity· $500M
Leadership Team
Andrew Guggenhime
President & Chief Financial Officer
Jeff Fairman
Founder and Vice President, Research
Recent News
Pharma Letter
2026-01-25
2026-01-23
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