10x Genomics · 15 hours ago
Sr. Scientist, Clinical Bioinformatics
Pleasanton, California, USA HQ
Full-time
Onsite
Senior Level
$158K/yr - $214K/yr
5+ years exp10x Genomics is establishing a diagnostics effort, translating their leading single-cell and spatial assay technologies into impactful clinical applications. They are seeking a Sr. Scientist to join the clinical bioinformatics team, focusing on implementing computational methods and deriving insights from large-scale datasets to enhance clinical diagnostics.
Biotechnology
Responsibilities
Implement rigorous computational/statistical methods for single-cell and spatial transcriptomics data analysis
Derive actionable insights from clinical/translational single-cell or in-situ spatial datasets
Design, implement and validate biomarkers for diagnostic applications
Implement and maintain bioinformatics pipelines for reproducible, large-scale data processing
Process and analyze single-cell or in-situ spatial transcriptomics datasets spanning hundreds to thousands of samples
Qualification
Required
Ph.D. in bioinformatics, computational biology, genomics or a related discipline with extensive hands-on experience in single-cell NGS data analysis
A minimum of 5 years of industry experience post Ph.D
Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers
In-depth understanding of the assumptions, limitations and caveats of statistical methods
Experience developing and optimizing high-performance, scalable code
Proficiency working in a Linux environment
Goal-oriented, self-motivated and an independent problem solver
Meticulous attention to detail and a conscientious work ethic
Preferred
Hands-on experience with 10x Genomics single-cell and in-situ transcriptomics technologies is a strong preference
Hands-on research experience in cancer or autoimmune diseases is a strong preference
Knowledge of clinical genomics, biomarker discovery and diagnostics
Development of statistical models and algorithms for single-cell or spatial transcriptomics data
Application of machine learning, particularly in the context of genomics
Proficiency with workflow orchestration frameworks such as Snakemake, Nextflow or Martian
Programming best practices including data analysis reproducibility, version control, design patterns, testing, debugging and profiling
Track record of writing production-level code or maintaining published software packages
High-throughput computing infrastructure such as HPCs or cloud computing
Benefits
10x’s equity grants
Comprehensive health and retirement benefit programs
Annual bonus program
Sales incentive program
Company
10x Genomics
Cells are the basic unit of life.
1001-5000 employees
H1B Sponsorship
10x Genomics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (41)
2024 (40)
2023 (35)
2022 (52)
2021 (34)
2020 (16)
Funding
Current Stage
Late StageLeadership Team
Serge Saxonov
Co-founder and CEO
Eric Whitaker
Executive Vice President and Chief Legal Officer
Recent News
2024-05-07
2024-04-30
2024-04-08
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