Immunome, Inc. · 15 hours ago
Senior Research Scientist, Yeast Display
Bothell, WA
Full-time
Onsite
Senior Level, Lead/Staff
$132K/yr - $163K/yr
8+ years expImmunome, Inc. is a clinical-stage targeted oncology company committed to developing innovative cancer therapies. They are seeking a highly skilled Senior Research Scientist to lead yeast display antibody discovery capabilities, focusing on library design, selection strategies, and hit identification.
BiopharmaBiotechnologyMedicalPharmaceutical
Responsibilities
Design, build, and optimize yeast display antibody libraries, including synthetic and immune-derived formats
Execute and oversee all stages of library construction, including cloning, transformation, expression assessment, and quality control
Plan, perform, and continuously improve MACS- and FACS-based selection strategies
Lead hit deconvolution using next-generation sequencing and sequence enrichment analyses
Conduct downstream characterization including expression testing, biophysical assays, and flow cytometry
Analyze complex datasets and communicate findings to cross-functional teams
Maintain detailed and accurate electronic laboratory notebooks
Collaborate across biology, protein engineering, chemistry, pharmacology, and translational teams
Qualification
Required
Bachelor's degree with a minimum of 12 years of relevant experience; or Master's degree with a minimum of 8 years; or Ph.D. with a minimum of 2 years of experience
Significant experience in drug discovery with deep expertise in yeast display technologies
Multiple years of hands-on experience in yeast display library construction, selections, and downstream characterization
Advanced proficiency with Benchling and related data management systems
Subject matter expertise in yeast display and antibody discovery platforms
Strong analytical and data interpretation skills
Exceptional organizational and documentation skills
Excellent written and verbal communication skills
Ability to manage multiple projects in a fast-paced, collaborative environment
Preferred
Phage display experience is a plus
Company
Immunome, Inc.
Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted therapies designed to improve outcomes for cancer patients.
51-200 employees
H1B Sponsorship
Immunome, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
Funding
Current Stage
Public CompanyTotal Funding
$998.85MKey Investors
JPEO-CBRNDU.S. Department of DefenseRobin Hood Ventures
2025-12-16Post Ipo Equity· $400M
2025-01-29Post Ipo Equity· $150M
2024-02-13Post Ipo Equity· $230M
Leadership Team
Clay Siegall
President and CEO
Purnanand D. Sarma
President & CEO
Recent News
2026-01-09
BioWorld Financial Watch
2025-12-19
Company data provided by crunchbase