Merck · 14 hours ago
Senior Scientist, In Vivo Cardiovascular Disease
South San Francisco, CA
Full-time
Onsite
Mid, Senior Level
$131K/yr - $207K/yr
1+ years expMerck is seeking an innovative and highly motivated Senior Scientist to join their Cardiometabolic Disease department in South San Francisco. The role involves identifying and advancing drug targets for cardiovascular diseases, designing experiments, and collaborating with cross-functional teams.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Design and execute experiments independently in the laboratory for target identification and validation utilizing in vivo preclinical models of cardiovascular disease
Be a team-player, working productively and collaboratively in cross-functional teams within and outside of our Company Research Laboratories to advance drug targets for cardiovascular disease
Communicate experimental results with stakeholders effectively and present research findings internally and at external scientific conferences
Stay apprised of latest scientific advances in the field
Learn and establish novel platforms and cutting-edge technologies to advance drug discovery efforts
Document research activities using electronic lab notebooks and contribute to scientific publications and technical reports
Qualification
Required
Ph.D. degree in cell biology, molecular biology, physiology, or related discipline with at least one (1) year of relevant experience
Hands-on experience working with rodents and development of animal models of cardiovascular disease (e.g., heart failure, atherosclerosis, atrial fibrillation, hypertension)
Direct involvement with efficacy readouts such as echocardiography to assess cardiac function
Proven ability to solve complex problems by undertaking innovative approaches and applying state-of-art technologies
Proficiency in standard molecular and cellular biology techniques, ex vivo sample processing and analysis
Able to work independently to design and execute experiments, interpret experimental data appropriately and proficiently, and present to teams within and outside the disease area
High level of organizational skills to support multiple projects
Excellent oral and written communication skills, having necessary people skills, and being able to work effectively in a matrixed environment
Preferred
Strategic thinker with in-depth knowledge of cardiovascular disease pathophysiology
Experience in one or more of the following areas: target identification & validation, cardiovascular disease, kidney disease, inflammation or lipid metabolism
Experience with primary cell culture models of cardiac function and cell-based assays
Basic understanding of the translatability of animal models to human cardiovascular disease and biomarker strategies
Strong quantitative skills, proficiency in data analysis and application of statistical methods
Familiarity with OMICs approaches
Benefits
Medical
Dental
Vision healthcare and other insurance benefits (for employee and family)
Retirement benefits, including 401(k)
Paid holidays
Vacation
Compassionate and sick days
Company
Merck
Merck is a biopharmaceutical company that offers medicines and vaccines for various diseases.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$5.59MKey Investors
Private Capital AdvisorsGavi, the Vaccine Alliance
2018-11-25Post Ipo Equity· $0.59M
2016-01-21Series Unknown· $5M
1980-12-19IPO
Leadership Team
Betty Larson
Executive Vice President and Chief Human Resources Officer
Dean Li
Executive Vice President and President, Merck Research Laboratories
Recent News
2026-01-24
2026-01-23
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