Mass General Brigham · 1 week ago
Postdoc Research Fellow Syynaptic and Network Dev Team
Boston-MA
Full-time
Onsite
Senior LevelMass General Brigham is a not-for-profit organization dedicated to advancing patient care, research, teaching, and community service. They are seeking a Postdoctoral Research Associate to work on deriving neuronal organoid cultures from human iPSCs and applying CRISPR gene editing technologies to study Rett syndrome and related neurodevelopmental disorders. The role involves close collaboration with experts, leading research efforts, and contributing to scientific publications and grant applications.
Health CareHome Health CareMedical
Responsibilities
Work closely with experts in human stem cell to create autism and related neurodevelopmental disorders (NDD) disease models in human cerebral organoids from patient-derived iPSC lines
Lead generation and maintenance of human cerebral organoids in our laboratory
Perform multi-electrode array (MEA) recordings and analyze network activity in the NDD and control human cerebral organoids
Work closely with team members in our interdisciplinary collaborations on the development and application of methods for human organoids, network recordings and network analysis
Ensure validity and reliability of all data collected and analyzed
Keep excellent records of experiments, undertake thorough data analysis and make active contributions to the laboratory research environment
Write regular internal reports as agreed and draft and/or contribute to reports for submission to research sponsors
Prepare and present findings at internal group meetings
Draft publications and/or presentations for scientific journals/conferences
Contribute to research grant applications
Provide guidance to staff and students, including training to students and/or other trainees
Be an active team member and set positive examples for other team members
Contribute and lead administrative tasks related to research and teaching goals
Maintain a safe workplace and follow all lab and hospital practices and procedures
Any other duties commensurate with the post as directed by the PIs
Qualification
Required
PhD degree (or about to be awarded at PhD) in one of the following fields: neuroscience, physiology, stem cell biology, molecular or cellular biology, or bioengineering
Available to start as soon as possible
A PhD in a relevant field
Research expertise sufficient to work independently: Generation and maintenance of human iPSC-derived brain organoids
Ability to work effectively and collaboratively with other group members
Superior written and verbal communication skills for working collaboratively, including communicating progress and challenges to PIs
Rigorous scientific skills for acquiring, analyzing and presenting data
Excellent time and project management skills
Ability to make independent decisions and solve routine problems encountered in research projects
Meticulous record keeping for both experimental procedures and for analysis
Willingness to adjust working hours in accordance with experimental demands and as necessary for project goals
Generosity of spirit and willingness to share and help develop skills in others
Preferred
Research expertise in CRISPR and/or other gene editing technologies for human iPSCs or embryonic stem cells (ESCs)
Research experience in neurophysiology (i.e., multielectrode array recordings and/or whole-cell patch clamp technique)
Research experience in computational analysis of network activity
Company
Mass General Brigham
Mass General Brigham specializes in providing medical treatments and health diagnostics services.
Founded in 1994
10001+ employees
H1B Sponsorship
Mass General Brigham has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (77)
2024 (61)
2023 (93)
2022 (70)
2021 (80)
2020 (29)
Funding
Current Stage
Late StageLeadership Team
E
Erin Flanigan
SVP, Human Resources, Community, Specialty Hospital Division
O’Neil A. Britton
Chief Integration Officer, Executive Vice President
Recent News
Research & Development World
2026-01-25
Longevity.Technology
2026-01-24
Company data provided by crunchbase