Sangamo Therapeutics, Inc. · 3 hours ago
Vice President, Quality
Brisbane, CA
Full-time
Hybrid
Director/Executive
$318K/yr - $354K/yr
15+ years expSangamo Therapeutics is a genomic medicine company focused on treating debilitating neurological diseases. The Vice President of Quality leads the Quality organization and is accountable for ensuring appropriate Quality oversight for the company, managing GxP operations and developing the Quality teams.
BiotechnologyGeneticsHealth CarePharmaceuticalTherapeutics
Responsibilities
Serve as accountable Quality leader and a member of the Technical Operations Leadership Team, operating at the executive level, and representing the company externally, as needed
Develop and execute a quality strategy that aligns with corporate objectives and focuses on fostering a culture of quality and continuous improvement
Lead preparation for and management of regulatory inspections (FDA, EMA, MHRA, etc.) across GMP, GCP, and GLP functions
Lead a team which has oversight for the following activities:
Generation and approval of policies, procedures, and training requirements in line with the Sangamo Quality System and activities
R&D and Clinical Quality Assurance (CQA) including managing compliance from preclinical to commercialization in relation to ICH E6 GCP, Good Laboratory Practices (GLPs), Good Pharmacovigilance Practices (GPVP’s) and other related activities to deliver on Sangamo’s clinical goals and regulatory obligations
Quality assurance and compliance for internal and external manufacturing related to Good Manufacturing Practices (GMP’s), including the following:
Release of clinical and commercial product, including use of QPs for ex‑US release
Deviation and change control management
Review of GMP manufacturing and QC documents
Supplier quality management
Training curricula for GMP staff
Oversight of electronic systems used to support Quality activities
Build, develop and coach the Quality team members
Maintain clear communication with project teams to ensure timely dissemination of information (product disposition, significant quality events including serious breaches, etc.)
Facilitate authorship and review of CMC sections for regulatory submissions
Track project activities, deliverables, and completion relative to budgets and company objectives
Support strategic planning by timely communicating Quality deliverables, constraints, risks and options, and collaborating with Technical Development, Program Management, Clinical, Commercial, Supply Chain, and internal and external Manufacturing teams
Identify risks and assumptions in plans, anticipate problems, and plan for contingencies. Remove obstacles to move work forward and/or to get efforts back on track
This position reports to the Chief Technical Officer (CTO) with a dotted line reporting responsibility to the Chief Executive Officer CEO). The VP is required to keep the CTO, CEO, and the Executive Leadership Team (ELT) updated on any major compliance risk that could threaten Sangamo, Sangamo’s patients, or Sangamo stakeholders
Qualification
Required
Bachelor's degree in life science or engineering field; an advanced degree is preferred
15+ years related experience in the biotechnology or pharma industry, ideally for Advanced-therapy Medicinal Products (ATMPs) including gene-based and gene editing therapies. Advanced knowledge of drug development process with direct experience with gene-based and rAAV-based therapies preferred
8+ years' experience in GxP Quality role, leading people and team management. Preference given to candidates with leadership oversite experience in GCP, GMP, GLP and GPVP
Ability to operate at the executive level and represent the company internally and externally
Proven ability to effectively develop, communicate, and gain support for execution plans and strategies with a wide range of stakeholders at the executive level
Experience leading regulatory inspections, managing GCP audit programs and managing inspection readiness programs cross-functionally
Leadership and management skills to grow and manage a high performing Quality organization
Demonstrated skills in project management and working with vendors and contractors
Expert background in FDA, ISO, EMA, GMP and ICH requirements ideally for ATMPs
Proven experience with regulatory submissions, ideally for products which were ultimately approved for commercial distribution, and regulatory inspections
Strong planning and tracking skills, able to see the big picture, well-organized, focused on results, capable of managing multiple projects, excellent time management with respect to priorities and self-management
Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills
Preferred
Advanced degree in life science or engineering field
Experience with gene-based and rAAV-based therapies
Excellent interpersonal skills
Excellent written and oral communication skills
Ability to work in a fast paced and dynamic environment that will require outstanding organization skills, and management of several competing priorities while driving all projects forward and meeting program/project deliverables
Stature, gravitas, and confidence to gain credibility and respect of peers
Self-reliant, a good problem solver and results-oriented
Energetic, flexible, collaborative and proactive; a leader who can positively and productively impact initiatives
Ability to work in both our Brisbane, CA and Richmond, CA sites. It is anticipated that the Brisbane, CA site will be decommissioned in 2026
Ability to travel 10%, domestically
Company
Sangamo Therapeutics, Inc.
For Sangamo Therapeutics, science is a means to develop new medicines with the potential to transform the lives of patients living with serious genetic diseases.
201-500 employees
H1B Sponsorship
Sangamo Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (3)
2023 (7)
2022 (14)
2021 (14)
2020 (8)
Funding
Current Stage
Public CompanyTotal Funding
$569.1MKey Investors
California Institute for Regenerative MedicineNational Institutes of Health
2025-05-12Post Ipo Equity· $23M
2024-03-22Post Ipo Equity· $24M
2019-04-03Post Ipo Equity· $145.5M
Leadership Team
Sandy Macrae
Chief Executive Officer
Prathyusha Duraibabu
Chief Financial Officer
Recent News
2025-12-02
Sangamo Therapeutics, Inc.
2025-12-02
Company data provided by crunchbase