Yoh, A Day & Zimmermann Company · 8 hours ago
Senior Research Scientist, Biophysics
South San Francisco, CA
Contract
Onsite
Mid, Senior Level
$70/hr - $80/hr
3+ years expYoh, A Day & Zimmermann Company is seeking a skilled Senior Research Scientist in Biophysics to join their Lead Discovery team. This lab-based role focuses on the biophysical and mechanistic characterization of small molecule-protein interactions to support the drug discovery pipeline.
Bookkeeping and PayrollConsultingStaffing Agency
Hiring Manager
Emily Aubuchon
Responsibilities
Design and execute binding characterization studies using SPR (Biacore S200 and 8K+)
Conduct routine compound screening and mechanistic studies using biophysical assays (e.g., nanoDSF, DLS, Spectral Shift)
Manage and coordinate outsourced biophysical studies with CROs
Analyze and interpret data to support SAR and lead optimization across multiple projects
Maintain detailed experimental records and present findings in internal meetings and reports
Qualification
Required
PhD in Biophysics, Biochemistry, or a related field
Minimum 3 years of relevant industry experience in small molecule drug discovery biophysics
Proven expertise in SPR assay development and data interpretation
Demonstrated expertise in designing, developing, and interpreting biophysical characterization of small molecule-protein interactions by SPR
Strong familiarity with additional biophysical techniques (TSA, DLS, Spectral Shift, NMR, ITC, etc.)
Preferred
Proficiency with data analysis and graphing tools is a plus
Benefits
Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
Health Savings Account (HSA) (for employees working 20+ hours per week)
Life & Disability Insurance (for employees working 20+ hours per week)
MetLife Voluntary Benefits
Employee Assistance Program (EAP)
401K Retirement Savings Plan
Direct Deposit & weekly epayroll
Referral Bonus Programs
Certification and training opportunities
Company
Yoh, A Day & Zimmermann Company
At Yoh, we focus on helping you precisely navigate and fulfill your talent demands.
1001-5000 employees
H1B Sponsorship
Yoh, A Day & Zimmermann Company has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (57)
2024 (28)
2023 (27)
2022 (25)
2021 (28)
2020 (27)
Funding
Current Stage
Late StageLeadership Team
Peter Melomo
Vice President, Sales Strategy & Professional Consulting Services
Tom Enright
VP Recruiting - Specialty Practices
Recent News
Philadelphia Business Journal
2025-01-11
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