Keros Therapeutics · 1 day ago
Scientist, Kidney Fibrosis
Lexington, Massachusetts, United States
Full-time
Onsite
Mid, Senior Level
$146K/yr - $164K/yr
2+ years expKeros Therapeutics is a public, clinical-stage biopharmaceutical company focused on developing therapies that target TGF-ß signaling pathways. They are seeking a Scientist to join their preclinical research team, where the candidate will contribute to studies on kidney fibrosis in chronic kidney diseases by developing models and evaluating novel treatments.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Develop, optimize and execute mouse models of kidney fibrosis, such as unilateral ureteral obstruction and 5/6 nephrectomy
Independently design and execute translatable in vivo experiments to generate pharmacokinetic and pharmacodynamic profiles and evaluate drug efficacy
Utilize a broad array of laboratory techniques to identify, validate and evaluate translatable disease relevant biomarkers
Analyze and interpret data within the broader context of CKD and inform next steps in the drug discovery/development process
Prepare and present detailed reports, publications, and presentations for internal and external stakeholders
External outreach to the broader scientific community (e.g., academic laboratories and contract research organizations) to build professional relationships and collaborations and expand our research capabilities
Stay abreast of the latest scientific advancements and incorporate new knowledge into ongoing projects
Draft IACUC protocols and amendments and maintain the highest standards of animal welfare
Contribute to the preparation of study reports, regulatory filings and project presentations
Maintain excellent written documentation of completed experiments (e.g., electronic lab notebook and study reports)
Qualification
Required
Knowledge of chronic kidney disease, translatable disease models and clinically relevant biomarkers
Excellent animal handling skills, including dosing using multiple routes of administration, biological sample and tissue collection and aseptic surgery techniques
Strong analytical and problem-solving skills, including data and statistical analysis
Ability to lead complex research projects and drive them to completion
Excellent organizational and project management skills
Effective communication skills, with experience in writing scientific publications and presenting data internally and externally
Highly collaborative working style and ability to adapt in a fast-paced environment
Ph.D. in Biology or a related field with 2+ years of experience, a Master's degree with 6+ years of relevant experience, or a Bachelor's degree with 10+ years of relevant experience
Preferred
Ability to independently lead research projects and drive successful outcomes
Experience with mammalian cell culture and in vitro model development (e.g., complex cellular models)
Extensive knowledge of TGF-β signaling pathways
Experience managing/mentoring junior associates
Company
Keros Therapeutics
Keros is a clinical-stage biopharmaceutical company focusing on the discovery, development, and commercialization of novel treatments.
51-200 employees
H1B Sponsorship
Keros Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (2)
2023 (1)
2022 (3)
2021 (1)
Funding
Current Stage
Public CompanyTotal Funding
$379.5MKey Investors
Pontifax
2024-01-03Post Ipo Equity· $140M
2020-11-13Post Ipo Equity· $149.5M
2020-04-07IPO
Leadership Team
Lorena Lerner
Chief Scientific Officer
Recent News
Keros Therapeutics, Inc.
2025-11-21
2025-11-20
Keros Therapeutics, Inc.
2025-11-19
Company data provided by crunchbase