Natera · 9 hours ago
Senior Generative AI Engineer
United States
Full-time
Remote
Senior Level, Lead/Staff
$125K/yr - $156K/yr
8+ years expNatera is a global leader in cell-free DNA testing, dedicated to oncology, women’s health, and organ health. They are seeking a Senior Generative AI Engineer to design, build, and deploy Generative AI and Machine Learning solutions that improve patient outcomes and clinical innovation.
BiotechnologyGeneticsHealth DiagnosticsMedicalWomen's
Responsibilities
Design, build, and operate LLM-powered systems used in production, from initial design through deployment and iterations
Build scalable agentic AI automation solutions, selecting appropriate patterns (reasoning, memory, agent frameworks, MCP’s, workflow orchestration, fine-tuning) based on business requirements
Implement GenAI patterns such as RAG, tool/function calling, and multi-step workflows, selecting approaches based on accuracy, reliability and cost
Develop and maintain data ingestion and retrieval pipelines, especially for unstructured or semi-structured documents
Fine-tune and adapt open-source or commercial LLMs for domain-specific tasks when appropriate
Set quality, evaluation, and reliability standards for GenAI systems, including testing, monitoring, observability, and failure handling
Make system-level tradeoffs across model choice, latency, cost, accuracy, and operational complexity, and guide teams through those decisions
Deploy and monitor GenAI services on AWS, optimizing for latency, cost, and system stability
Collaborate with product managers and domain experts to translate requirements into technical solutions
Establish golden paths (templates, examples, docs) and contribute to shared GenAI libraries, patterns, and best practices used by other engineers
Provide technical guidance and mentorship to mid-level engineers
Qualification
Required
8+ years of experience in software engineering, ML engineering, or applied AI
Proven experience building and operating LLM-based systems in production
Strong Python skills and experience with PyTorch and/or Hugging Face
Experience building agentic AI solutions using agent frameworks (LangChain, CrewAI etc.) and agent execution engines (AWS Bedrock etc.)
Solid understanding of RAG architectures, embeddings, vector databases, and prompt orchestration
Experience deploying AI systems on AWS (e.g., SageMaker, Bedrock, EKS/ECS, Lambda, S3)
Strong debugging skills and comfort working across model, data, and infrastructure layers
Ability to work independently on complex problems and communicate clearly with cross-functional partners
Preferred
Masters degree or PhD in Computer Science, AI/ML, engineering or related field
Experience in healthcare, pharma, diagnostics, or other regulated industries
Familiarity with AI governance frameworks, bias detection, explainability, and compliance (e.g., HIPAA, CLIA, FDA)
Benefits
Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
Free testing in addition to fertility care benefits
Pregnancy and baby bonding leave
401k benefits
Commuter benefits
Generous employee referral program
Company
Natera
Natera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health.
5001-10000 employees
H1B Sponsorship
Natera has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (90)
2024 (72)
2023 (37)
2022 (71)
2021 (64)
2020 (40)
Funding
Current Stage
Public CompanyTotal Funding
$1.16BKey Investors
Sofinnova InvestmentsLightspeed Venture PartnersSequoia Capital
2023-09-07Post Ipo Equity· $250M
2022-11-15Post Ipo Equity· $400.05M
2022-03-16Post Ipo Equity· $5M
Leadership Team
Steve Chapman
CEO
Jonathan Sheena
Co-Founder, Board Member
Recent News
2026-01-22
Business Wire
2026-01-22
2026-01-22
Company data provided by crunchbase