BiomeSense · 1 day ago
Senior Bioinformatics Engineer
Chicago, IL
Full-time
Onsite
Mid, Senior Level
$125K/yr - $200K/yr
3+ years expBiomeSense is a pioneering life sciences startup focused on harnessing the power of the gut microbiome to revolutionize personalized medicine. The Senior Bioinformatics Engineer will help build the MetaBiome platform, contributing to bioinformatics, data engineering, and product development while designing and maintaining robust infrastructure for microbiome data analysis.
AnalyticsBioinformaticsBiotechnologyHealth CareLife ScienceMedical
Responsibilities
Help design, implement, and maintain the robust, auditable backend required for the highest-quality extraction of clean microbiome data from raw shotgun metagenomic sequencing data
Contribute to the development and maintenance of cloud-based infrastructure, including databases, distributed computing workflows, and REST endpoints, supporting a data platform that organizes microbial sequence data and associated clinical metadata
Lead the design, execution, and documentation of reproducible computational experiments from concept to conclusion, including experimental design, data preparation, model selection, and evaluation strategies
Develop and implement novel analytical methodologies and algorithms informed by experimental findings and validated through rigorous evaluation
Design, implement, and maintain robust data ingestion interfaces leveraging external APIs and clinical ontologies such as SNOMED, MedDRA, and ICD-10, adhering to software engineering best practices including wireframe design, unit testing, version control, code review, and security and compliance
Qualification
Required
B.S. /M.S. /PhD in Computational Biology, Bioinformatics, Computer Science or a related field with 3+ yrs industry experience (biotech start-up ideal)
Strong proficiency in Python and JavaScript, with experience building scalable, reusable, testable, and maintainable software
Proficiency with PostgreSQL or other relational SQL database systems
Familiarity with clinical ontologies such as SNOMED, ICD-11, ATC, and LOINC
Familiarity with Amazon Web Services and best practices in computer security
Proficiency with one or more modern frontend web technologies
Excellent communication skills for presenting complex scientific concepts to diverse stakeholders
Strong ownership mindset and the ability to execute in fast-moving environments
Strong fundamentals in bioinformatics pipelines, QC, and reproducibility
Preferred
Bioinformatician with experience working with NGS data and bioinformatics pipeline verification and knowledge of microbiome-specific challenges (compositional data, variability, confounders)
Familiarity with longitudinal / repeated-measures biological datasets
Experience integrating external ontologies or standardized vocabularies
Exposure to cloud infrastructure, workflow orchestration, or containerization
Interest in AI/ML applications built on large biological datasets
Company
BiomeSense
BiomeSense is a developing novel technologies to enable continuous, at-home monitoring of the human microbiome.
2-10 employees
Funding
Current Stage
Early StageTotal Funding
$12.61MKey Investors
National Science FoundationBioX ClanPolsky Center at the University of Chicago
2025-08-12Seed
2023-12-19Series Unknown· $6.18M
2023-02-05Seed· $3M
Leadership Team
Dylan Nichols
CTO
Recent News
Google Patent
2024-04-15
Google Patent
2024-04-15
2023-05-18
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