Revolution Medicines · 1 day ago
Director of Pharmacometrics
Redwood City, California, United States
Full-time
Onsite
Lead/Staff, Director/Executive
$186K/yr - $233K/yr
5+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Director of Pharmacometrics will develop advanced statistical methodologies, support key development decisions, and collaborate cross-functionally to enhance quantitative science capabilities.
Health CareLife ScienceMedical
Responsibilities
Develop and apply advanced statistical and machine learning methodologies to address complex scientific questions in PK/PD and exposure-response analysis
Design and implement model-based meta-analysis (MBMA) frameworks to integrate internal PKPD data and external data to inform clinical pharmacology strategies
Provide statistical and quantitative modeling support for key development decisions, including dose optimization and RP2D selection
Collaborate cross-functionally to ensure modeling approaches are scientifically rigorous, fit-for-purpose, and aligned with program objectives
Contribute to the continuous advancement of quantitative science capabilities, including method development, best practices, and adoption of innovative analytical approaches
Qualification
Required
PhD in Statistics/Biostatistics, Pharmaceutical Sciences or MS in Statistics with five years of experience in MBMA in pharmaceutical industry
Solid knowledge and hands-on experience in hierarchical models and Bayesian inference are required
Solid knowledge and hands-on experience in standard statistical modeling (generalized linear models, survival models, mixed models, etc) are required
Demonstrated experience in meta-analysis, including the application of appropriate statistical methods to model between-study variabilities
Proficiency in statistical programming using R
Excellent verbal and written communication skills, and ability to clearly convey complex concepts and findings to both non-specialist and specialist audiences
Experience and track record in clinical-stage drug development
Preferred
Prior experience with small molecules in oncology drug development
Local candidates are preferred, but strong remote candidates will be considered
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
Pharmaceutical Technology
2026-01-13
Company data provided by crunchbase