Vertex Pharmaceuticals · 15 hours ago
Immunology Principal Research Associate
Seattle, WA
Full-time
Onsite
Senior Level, Lead/Staff
$93K/yr - $139K/yr
2+ years expVertex Pharmaceuticals is a global biotechnology company that invests in scientific innovation. They are seeking a highly motivated Principal Research Associate to contribute directly to research efforts by designing, executing, and analyzing experiments related to immune mechanisms, target validation, and therapeutic development.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Isolate, culture, and manipulate primary human immune cells and cell lines
Design and execute experiments to interrogate immune cell phenotype and function, including cell-based multicolor flow cytometry and Incucyte assays
Troubleshoot experiments and optimize protocols
Collect, analyze, and interpret experimental data while maintaining accurate and detailed laboratory records
Collaborate with scientists across discovery teams to achieve project goals
Prepare data for internal reports and presentations for internal meetings
Perform other duties as needed
Qualification
Required
Isolate, culture, and manipulate primary human immune cells and cell lines
Design and execute experiments to interrogate immune cell phenotype and function, including cell-based multicolor flow cytometry and Incucyte assays
Troubleshoot experiments and optimize protocols
Collect, analyze, and interpret experimental data while maintaining accurate and detailed laboratory records
Collaborate with scientists across discovery teams to achieve project goals
Prepare data for internal reports and presentations for internal meetings
Perform other duties as needed
Hands-on tissue culture experience, including the isolation and maintenance of primary human immune cells and human cell lines
Experience with nucleic acid techniques to quantify gene expression such as PCR, qPCR, and RNA sequencing
Experience with a variety of cell-based immunology assays to interrogate immune cell phenotype and function including multicolor flow cytometry and Incucyte assays
Experience measuring soluble analytes such as by ELISA, Luminex, or MSD
Critical thinking and self-reliance to solve tasks independently or ask questions
Strong organizational skills and attention to detail
Willingness and ability to work in a highly collaborative environment
Foundational knowledge of immunology and an eagerness to learn new techniques and skills
Strong analytical skills and proficiency in the following software packages: Microsoft Office, GraphPad Prism, FlowJo and Methodical Mind Analysis Software
Master's degree (or equivalent degree) in biological sciences and 2+ years of relevant employment experience, or
Bachelor's Degree (or equivalent degree) in biological sciences and 5+ years of relevant employment experience
Benefits
Annual bonus
Annual equity awards
Overtime pay
Medical, dental and vision benefits
Generous paid time off (including a week-long company shutdown in the Summer and the Winter)
Educational assistance programs including student loan repayment
Generous commuting subsidy
Matching charitable donations
401(k)
Company
Vertex Pharmaceuticals
Vertex Pharmaceuticals is focused on the discovery and development of small molecule drugs for the treatment of serious diseases.
5001-10000 employees
H1B Sponsorship
Vertex Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (188)
2024 (150)
2023 (111)
2022 (164)
2021 (112)
2020 (80)
Funding
Current Stage
Public CompanyTotal Funding
$657.31MKey Investors
Janssen Belgium
2024-07-10Post Ipo Secondary· $1.11M
2022-05-17Post Ipo Equity· $50M
2009-12-03Post Ipo Equity· $443M
Leadership Team
Reshma Kewalramani
CEO and President
Nina Devlin
Senior Vice President, Chief Communications Officer
Recent News
2026-01-16
Pharmaceutical Technology
2026-01-15
2026-01-13
Company data provided by crunchbase