Centessa Pharmaceuticals · 16 hours ago
Director, Biostatistics
Boston, MA
Full-time
Hybrid
Director/Executive
$190K/yr - $250K/yr
10+ years expCentessa Pharmaceuticals plc is a new kind of pharmaceutical company focused on data-driven decision-making in a deconstructed R&D environment. As the Director of Biostatistics, you will oversee clinical development planning and execution, ensuring statistical strategies align with clinical objectives and regulatory expectations while leading statistical analyses and influencing clinical development strategy.
BiotechnologyPharmaceutical
Responsibilities
Lead biostatistics efforts in a team setting and focus on business priorities
Collaborate on clinical development plan for one or more molecules to provide biostatistical perspective and insight
Determine innovative study designs, appropriate statistical tests and methods for evaluating and generating statistical hypotheses to meet study and regulatory requirements
At study level, author and review statistical sections for protocols, statistical power and sample size estimate, randomization schemes, clinical study reports, and regulatory submission documents
Lead the planning, organization and analysis of different data sources to enable delivery of the statistical analysis plan and clinical study endpoints for assigned products
Work with cross-functional team to develop ad hoc analysis plans and ensure analyses are performed appropriately by programming staff
Lead and guide third-party statistical vendors and contractors in the execution of relevant deliverables (eg, TLFs, SAPs, blinding plans)
Oversee preparation, conduct, and execution for Data Monitoring Committee meetings
Maintain expertise in state-of-the-art statistical methodologies and statistical analyses
Collaborate with Data Management to ensure data integrity and quality
Qualification
Required
PhD in Statistics or Biostatistics
10+ years of post-PhD experience applying statistical methods in the pharmaceutical industry
Demonstrated experience supporting late-stage (registrational) trials, including experience with regulatory submissions
Ability to use SAS and/or R programming languages to perform analyses, conduct statistical modeling, and validate important data derivations
Hands-on experience working with CDISC standards and programming based on raw datasets, SDTM, and ADaM datasets
Ability to work in a cross-functional matrix environment, and proactively influence teams with innovative clinical development strategy
Demonstrates breadth of diverse leadership experiences and capabilities including: the ability to develop and coach other colleagues to achieve meaningful outcomes and create business impact
Consistently demonstrates strong oral and written communication skills
Preferred
Knowledge and experience in neurology and/or oncology therapeutic areas preferred
Experience of interacting with regulatory agencies, including FDA and EMA, highly desirable
Benefits
Discretionary annual bonus
Participation in our equity program
401(k) plan
Company-sponsored medical, dental, vision, and life insurance
Generous paid time off
Health and wellness program
Company
Centessa Pharmaceuticals
Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process.
51-200 employees
H1B Sponsorship
Centessa Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.12BKey Investors
Oberland Capital
2025-11-11Post Ipo Equity· $250M
2024-09-11Post Ipo Equity· $225M
2024-04-23Post Ipo Equity· $100M
Leadership Team
John Crowley
Chief Financial Officer
Gregory Weinhoff
Chief Business Officer
Recent News
2026-01-05
2025-12-14
Company data provided by crunchbase