Twist Bioscience · 14 hours ago
Sr Research Associate, Molecular Biology
USA - Quincy, MA
Full-time
Onsite
Mid, Senior Level
4+ years expTwist Bioscience is a company that synthesizes genes from scratch, aiming to revolutionize the genomics industry. They are seeking a motivated Senior Research Associate in Molecular Biology to support antibody discovery platforms and execute complex workflows involving wet lab experimental design and data analysis.
B2BBiotechnologyChemicalHealth CareLife Science
Responsibilities
Provide molecular biology support for antibody discovery platforms, including hybridoma and Beacon technologies
Perform high-throughput PCR-based techniques for gene amplification and sequence analysis using bioinformatics tools such as Geneious Biologics and Geneious Prime
Conduct antibody engineering workflows, including sequence optimization, humanization, and mutagenesis
Design DNA constructs for downstream applications including immunization, transient cell surface expression, and recombinant protein expression and purification
Independently design experimental plans, execute complex workflows, and analyze large-scale datasets
Concurrently execute multiple antibody discovery projects requiring wet lab activities, data analysis, report generation and preparation of deliverables
Record and communicate experimental details, draft reports, and deliver data with a high level of integrity and ethics
Qualification
Required
Bachelor's degree in molecular biology, biochemistry, or a related discipline, and 4 - 5 years of related experience, or Master's degree with 3 years of related experience
Strong understanding of antibody discovery, preferably familiar with antibody structure and various antibody formats, including antibody fragments, bispecifics, nanobodies, scFvs, and antibody-drug conjugates (ADCs)
Previous experience utilizing molecular biology techniques including PCR, DNA purification and quantification, NGS, Sanger sequencing, and sequence analysis is required
Proficient in sequence analysis using platforms such as Geneious Biologics and Geneious Prime
Ability to effectively troubleshoot and optimize processes in order to meet a wide range of project needs
Ability to work independently, but also collaborate and effectively communicate within and across departmental teams
Exceptional written and verbal communication skills
Highly organized, detail oriented, and able to operate in a fast-paced and growing environment
Preferred
Industry experience is strongly preferred
Experience with primer design, recombinant protein expression, and plasmid construction is preferred
Experience in antibody engineering, including humanization, mutagenesis, and sequence optimization is preferred
Company
Twist Bioscience
Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.
501-1000 employees
H1B Sponsorship
Twist Bioscience has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (18)
2024 (14)
2023 (22)
2022 (19)
2021 (4)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$553.11MKey Investors
Capital World InvestorsBiomatics Capital PartnersIllumina
2022-02-09Post Ipo Equity· $250M
2020-01-27Post Ipo Equity· $50M
2018-10-30IPO
Leadership Team
Emily Leproust
CEO
Siyuan Chen
Chief Technology Officer
Recent News
Genetic Engineering News
2026-01-17
2026-01-16
Company data provided by crunchbase