Editas Medicine · 1 week ago
Oligonucleotide Scientist I, Process Development
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$115K/yr - $135K/yr
3+ years expEditas Medicine is pioneering the potential of CRISPR gene editing to develop transformative genomic medicines. The Oligonucleotide Scientist I will support the development and production of RNA-based gene editing components, managing vendor activities and synthesizing guide-RNA materials for research and clinical programs.
BiotechnologyGeneticsHealth CareMedical
Responsibilities
Manage external vendor activities to supply gRNA (research and GMP grades)
Provide subject expertise internally and externally regarding gRNA design, quality characteristics, and production processes
Prepare oligonucleotide synthesis reagents and synthesize, process, and purify guide-RNA using automated instruments as well as hands-on techniques
Analyze final products and intermediates, interpret data, and make independent process decisions
Desalt, concentrate, and lyophilize final gRNA material using scale-appropriate instrumentation or techniques
Coordinate with members of other teams and manage material requirements, priorities, and timelines
Present data and development strategies within the group and to cross-functional departments
Adapt as needed to meet the needs of the most critical project(s)
Assist with the coordination of instrument preventative maintenance and repairs
Maintain an electronic laboratory notebook and miscellaneous documentation
Maintain reagent inventory
Qualification
Required
PhD in Chemical Engineering, Chemistry, Pharmacy, Biochemistry or related discipline with 3 years relevant industry experience, Master's degree with 6+ years of relevant industry experience, or Bachelor's degree 8+ years of relevant industry experience
In-depth knowledge of DNA, RNA, and oligonucleotide design, production methods, impurities, and analytics
Experience with oligonucleotide synthesizers, specifically BioAutomation/LGC MerMade platforms
Experience with preparative-scale HPLC purification instruments
Experience with molecular-weight-cutoff (MWCO) desalting methods and/or UF/TFF instrumentation a plus
Experience with nucleic acid analytics, including HPLC, LCMS, and UV spectroscopy
Experience with aseptic / RNase-free handling and operation
Excellent time and project management
Ability to work effectively in a cross-functional team environment
Excellent oral and written communication skills
Technical troubleshooting and organizational skills
Proficient with Microsoft Office programs
Preferred
Prior experience managing external CRO and CDMO vendors is a plus
Experience in high throughput processing methodologies and automation is a plus
Benefits
Blue Cross Blue Shield PPO Medical Plan
Company-funded Health Savings Account
Dental and Vision Insurance
Life and Disability Insurance
Dependent Care Account
Tuition Reimbursement
401(k) plan with company match
Employee Stock Purchase Plan
Employee Assistance Plan
Wellness Programs
Flexible Paid Time Off policy
Company
Editas Medicine
Editas Medicine is a clinical-stage genome editing company that develops genomic medicines for serious diseases.
201-500 employees
H1B Sponsorship
Editas Medicine has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (19)
2023 (5)
2022 (8)
2021 (9)
2020 (16)
Funding
Current Stage
Public CompanyTotal Funding
$931.6MKey Investors
Boris NikolicJuno Therapeutics
2023-06-14Post Ipo Equity· $125M
2021-01-21Post Ipo Equity· $231M
2020-06-23Post Ipo Equity· $215.6M
Leadership Team
Gilmore O'Neill
CEO
Charlene Stern
Executive Vice President & General Counsel
Recent News
2025-11-21
Labiotech UG
2025-11-15
2025-11-11
Company data provided by crunchbase