OpenEye, Cadence Molecular Sciences · 2 hours ago
Intern--Scientific Developer, Target Exploration (R52858/dl)
OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design. This internship opportunity focuses on advancing computational approaches for understanding how cryptic pockets influence protein function through allosteric effects.
Responsibilities
Help develop and validate an algorithmic framework for predicting how the effect of binding at detected pockets propagates through the entire protein structure
Enabling users to identify which pockets are most likely to impact key functional regions
Developing and validating computational methods on well-characterized protein targets with known allosteric sites
Integrated into a larger workflow for connecting cryptic-pocket detection to functional interpretation of the ligand binding
Qualification
Required
Extensive programming experience
Strong scientific skills in problem-solving, protein structure analysis, and presenting key findings
Preferred
Current graduate students or advanced undergraduate students in computational biology, chemistry, biophysics, or related fields
Proficiency in Python
Familiarity with normal mode analysis
Solid understanding of linear algebra
Basic knowledge of linear response theory and/or the perturbation-response scanning method
Company
OpenEye, Cadence Molecular Sciences
OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and technology and design services across the drug discovery process.
H1B Sponsorship
OpenEye, Cadence Molecular Sciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (11)
2021 (4)
2020 (1)
Funding
Current Stage
Growth StageTotal Funding
unknown2022-07-25Acquired
Leadership Team
Recent News
2025-02-16
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