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Link Cell Therapies · 12 hours ago

Scientist (I/II), In Vivo Pharmacology

South San Francisco, CA

Full-time

Onsite

Mid, Senior Level

$130K/yr - $150K/yr

0+ years exp

Link Cell Therapies is developing innovative cell therapies for solid tumors. The Scientist will support In Vivo Pharmacology efforts, conducting studies with mouse tumor models and collaborating with other scientists to advance the company's therapeutic programs.

BiotechnologyLife ScienceMedical

Hiring Manager

Diego Vargas

Responsibilities

Independently execute •in vivo• studies to support preclinical characterization and evaluation of our programs using xenograft tumor models

Conduct hands-on •in vivo• experimental procedures including: dosing (intravenous , subcutaneous and intraperitoneal); caliper tumor measurements; blood and tissue collection, processing and analysis by flow cytometry; and bioluminescent imaging

Assist with •in vitro• tumor cell line expansion

Independently analyze, summarize and interpret experimental data

Collaborate and communicate with other scientists to align on key deliverables

Comply with IACUC regulations

Assist with vivarium operations, as needed

Ensure accurate and organized record-keeping of study data and maintain scientific documentation in an electronic lab notebook

Qualification

ImmunologyVivo StudiesFlow CytometryBioluminescent ImagingMicrosoft OfficeGraphPad PrismLiving ImageFlowJoWillingness to LearnAttention to DetailOrganizational SkillsTeam Collaboration

Required

BS (8+ years), MS (4-6 years) or PhD (0-4 years) in Immunology or a related life sciences field

Ability to execute technical procedures under minimal supervision with a high degree of integrity, consistency, and rigor, along with excellent organizational skills and attention to detail

Intrinsically motivated, with a willingness to learn and adopt new methodologies in a dynamic, fast-paced environment

Experience handling immunodeficient mice, with demonstrated expertise in techniques including intravenous tail vein injection, bioluminescent imaging, subcutaneous tumor implantation, intraperitoneal dosing, caliper tumor measurement, blood collection (terminal and non-terminal), cell culture, tissue harvest, and tissue processing and cell analysis by multicolor flow cytometry

Fluency with Microsoft Office, GraphPad Prism, Living Image and FlowJo