Research Fellow: Bioassay Development jobs in United States
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Biogen · 8 hours ago

Research Fellow: Bioassay Development

Biogen is seeking a highly motivated and creative Research Fellow to join the Bioassays and High-Throughput Screens group within the Synthetic Medicines Design department. The role involves designing and executing high-throughput biochemical and cell-based assays to support small-molecule discovery programs while collaborating with cross-functional teams.

BiotechnologyHealth CareNeuroscienceTherapeutics
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Design, develop, optimize, and execute high-throughput biochemical and cell-based assays to support small-molecule discovery programs across Hit ID, Lead ID, and Lead Optimization
Work closely and collaboratively with Medicinal Chemists, Project Teams, and other discovery functions to enable rapid DMTA cycles and drive SAR
Explore, evaluate, and implement novel assay platforms and technologies, including differentiated internal assays not readily available through external providers
Analyze, integrate, and clearly summarize large and complex datasets, translating assay outputs into actionable biological insight
Communicate results effectively through written reports, data packages, and oral presentations in project team and departmental forums

Qualification

High-throughput assay developmentBiochemical assaysCell-based assaysLiquid handling systemsMass spectrometry assaysAssay miniaturizationPublication recordCommunication skillsCollaborative teamwork

Required

Ph.D. in a relevant scientific field (i.e., analytical chemistry, biological sciences, biochemistry, pharmaceutical sciences, or molecular biology) and ability to commit to an 18-month long industry research fellowship onsite in Cambridge, MA
Hands-on experience developing and running high-throughput biochemical and cell-based assays in high throughput format
Proficiency with high-throughput liquid handling systems, plate readers, and automated screening workflows
Demonstrated ability to work independently with accountability, while also contributing effectively as part of a collaborative, multidisciplinary team
Excellent written and oral communication skills, with the ability to clearly convey complex data and scientific rationale

Preferred

Experience in assay miniaturization in 384- or 1536-well plate
Experience with mass spectrometry-based assays, including higher-throughput MS readouts for small-molecule and/or intact mass protein quantification (preferred)
Experience with assay platforms such as MSD, ELISA, and cell-based reporter assays using fluorescence (e.g., TR-FRET, HTRF) or luminescence
Experience developing kinetic or mechanistic assays to determine small-molecule parameters (e.g., kon, koff, kinact, KI)
Strong publication record in peer-reviewed scientific journals

Benefits

Medical, Dental, and Vision Insurance
Up to 15 days of paid accrued annual vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
Up to 12 company paid holidays + 3 paid days off for Personal Significance
80 hours of sick time per calendar year
401(k) program participation with company matched contributions
Employee stock purchase plan
Employee Resource Groups participation

Company

Biogen is an American biotechnology company that provides therapeutics for neurological, autoimmune, and rare diseases.

H1B Sponsorship

Biogen has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (100)
2024 (93)
2023 (101)
2022 (134)
2021 (104)
2020 (114)

Funding

Current Stage
Public Company
Total Funding
$1.5B
Key Investors
JP Morgan
2023-08-28Post Ipo Debt· $1.5B
1991-09-27IPO

Leadership Team

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Robin C. Kramer
Executive Vice President, Chief Financial Officer
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Priya Singhal
Executive Vice President, Head of Development
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Company data provided by crunchbase