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Absci · 21 hours ago

Senior Research Associate

Vancouver, WA

Full-time

Onsite

Mid, Senior Level

$88K/yr - $100K/yr

3+ years exp

Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. They are seeking a highly motivated and skilled Senior Research Associate to join their Pharmacology & Bioassays team, focusing on advancing preclinical drug discovery through executing cell-based assays and cell line engineering.

Artificial Intelligence (AI)BiopharmaBiotechnologyLife Science

Comp. & Benefits

No H1B

Responsibilities

Maintain and culture primary cell types, and run various in-vitro/ex-vivo assays contributing to the development of pharmacology work-packages

Contribute to design, development and hands-on execution of in-vitro and ex-vivo disease-relevant assays for MOA studies and therapeutic testing

Troubleshoot and refine assays, ensuring reproducibility and robustness in both medium- and high-throughput formats

Perform data analysis, interpret and present experimental data at various platforms

Collaborate with interdisciplinary teams, including cellular screening to integrate data from cell-based assays and support drug discovery goals

Contribute to the preparation of SOPs, study protocols, and data presentations for regulatory and internal purposes

Ensure adherence to best practices in assay development, data management, and experimental execution

Qualification

Primary cell cultureMechanistic assaysReporter cell-based assaysFlow cytometryData analysis softwareCollaborative team environmentCommunicationOrganizational skills

Required

BSc in Biology, Cell Biology, Immunology, Biotechnology, or related field with 5+ years of industry experience in cell-based assays and primary cell culture work, OR MSc with 3+ years of relevant industry experience

Hands-on experience in primary cell culture, including immune cells (PBMCs, T-cells, NK cells), cancer cell lines, and other disease-relevant models

Experience in mechanistic assays, such as MoA assays, ligand-binding assays, ADCC, CDC, ADCP, and cellular uptake assays

Experience in reporter cell-based assays, with the ability to develop and implement these assays

Experience with flow cytometry, ELISA, Western blot, qPCR, and multiplexing technologies

Proficiency in data analysis software such as GraphPad Prism, SoftMax Pro to interpret and visualize experimental results

Ability to troubleshoot assays, ensuring high-quality and reproducible data

Excellent communication skills, with the ability to present data effectively to a variety of stakeholders and contribute to decision-making

Strong organizational skills, with the ability to prioritize tasks and manage multiple projects simultaneously

Demonstrated success working in a matrixed, highly collaborative team environment, contributing to both individual and team goals