Spyre Therapeutics · 12 hours ago
Executive Director, Program Management
Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic diseases. The Executive Director of Program Management will play a crucial role in the planning and execution of development programs, ensuring alignment across functions and managing program risks.
BiotechnologyTherapeutics
Responsibilities
Meticulously maintain and track detailed integrated program timelines ensuring alignment across functions on dependencies and assumptions crucial for corporate goals. Recognize and alert stakeholders when projects are on or near critical paths to key milestones. Communicate progress transparently and address issues promptly
Manage cross-functional meetings efficiently, ensuring clear objectives, documenting outcomes, information, and action items, and following up on tasks with team members
Develop and upkeep project documentation including meeting materials, minutes, action item logs, decision trackers and dashboards
Proactively identify, monitor, communicate and propose mitigation options for program risks
Collaborate across functions including Pre-clinical, Clinical Development, Technical Operations, Regulatory, Quality, Finance and Legal to ensure alignment
Play a pivotal role within the Portfolio Management and Operations team, providing guidance on best practices, developing team resources, tools and templates, and nurturing a culture of excellence, innovation, and accountability
Other duties as assigned
Qualification
Required
Demonstrated proficiency in overseeing complex development programs, guiding them from Investigational new Drug (IND) stage through Phase 2 clinical development, with a strong preference for monoclonal antibody therapeutics experience
Bachelor's degree in a science-related field required; an advanced degree is preferred
Minimum of 10 years of relevant experience in biotechnology or pharmaceuticals, with at least 5 years directly in program management
Strong planning skills, critical thinking abilities and keen attention to detail
Ability to juggle multiple tasks, adapt to shifting priorities in a fast-paced environment
Excellent facilitation, communication, and leadership skills
Strong interpersonal skills and the ability to interact well with all employee levels
Expert in creating Gantt charts in Smartsheet, Think-Cell and Office Timeline Pro+ software, along with report generation
In-depth understanding of the drug development process, regulatory requirements, and industry standards
Willingness to travel up to 10% annually, including quarterly all hands meetings and ad hoc development team gatherings
Preferred
An advanced degree is preferred
Benefits
Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.
Unlimited PTO
Two, one-week company-wide shutdowns each
Commitment to provide professional development opportunities.
Remote working environment with frequent in-person meetings to address complex problems and build relationships.
Company
Spyre Therapeutics
Spyre Therapeutics is a biotechnology business that is developing a strong pipeline of antibody therapies.
Funding
Current Stage
Public CompanyTotal Funding
$835M2025-10-13Post Ipo Equity· $275M
2024-11-18Post Ipo Equity· $200M
2024-03-18Post Ipo Equity· $180M
Recent News
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2026-01-03
2025-12-01
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