Chief Information Security Officer jobs in United States
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Mayo Clinic · 22 hours ago

Chief Information Security Officer

Mayo Clinic is a top-ranked healthcare provider dedicated to putting patients first while supporting their employees with competitive compensation and benefits. The Chief Information Security Officer (CISO) is responsible for leading the global information security program, ensuring the protection of sensitive data and digital assets while fostering a culture of cybersecurity awareness across the organization.

BiotechnologyHealth CareHospitalMedicalWellness
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H1B Sponsor Likelynote

Responsibilities

Enterprise Information Security Leadership
Refresh and execute a comprehensive, forward-looking information security strategy that protects Mayo Clinic’s data, systems and intellectual property across all operations and geographies
Oversee all elements of Mayo Clinic’s enterprise-wide information security program, including policy, strategy, architecture and operations, threat intelligence, incident response, AI and automation, security testing, identity management, ERIS and ERP, ensuring alignment to regulatory requirements and industry standards
Champion adoption of advanced security technologies, such as AI-driven threat detection, zero trust architecture, cloud security and identity management platforms in a manner that supports operations
Continuously assess and adapt the security program to address emerging threats, digital transformation and the needs of a remote and hybrid workforce
Serve as a strategic partner to executive leadership and cross-functional teams, integrating security into business processes, technology initiatives and organizational change efforts
Foster a culture of cybersecurity awareness and shared accountability among employees, patients, partners and vendors
Collaborate with the DTO, internal audit, compliance, risk operations, legal, physical security, systems operations and development teams to coordinate security initiatives and drive enterprise-wide resilience while fostering and maintaining a positive user experience
Engage with external partners, industry groups and regulatory bodies to benchmark practices and ensure Mayo Clinic remains at the forefront of security innovation
Provide visionary leadership in risk management, governance and performance measurement, utilizing automation, advanced analytics, real-time dashboards and executive reporting
Guide the organization in balancing security, privacy and operational agility, ensuring business alignment and effective governance to safely enable emerging technology
Lead the development and monitoring of executive-level metrics, risk analysis, mitigation strategies and reporting mechanisms
Provide executive leadership for enterprise cyber incident and crisis management, ensuring decisive, coordinated response and recovery for security events impacting the organization at any time
Advise senior leadership on security risks, trends and investment priorities, supporting informed decision-making and continuous improvement
Ensure security objectives are continually evaluated and sufficient to address evolving risks and aligned to organizational risk tolerance
Build, mentor and retain a diverse, high-performing team of information security professionals, promoting continuous learning and professional development
Cultivate a culture of inclusion, innovation and excellence within the security function
Lead the evolution of the information security program, securing executive sponsorship and budget, demonstrating measurable value and driving consensus among functional leaders
Manage relationships with external technology vendors and professional services firms, overseeing evaluation, negotiation and ongoing performance of service agreements

Qualification

CISSP certificationInformation security strategyRisk managementTeam leadershipCloud securityData Loss PreventionIdentityAccess ManagementGovernanceRiskComplianceCybersecurity awarenessCollaborationCommunicationNegotiation

Required

Bachelor's degree in information technology, Health Informatics, Business Administration or related field is required
Master's degree of Science, Business Administration, Health Administration or related field is required
Qualified candidates must be a Certified Information Systems Security Professional (CISSP) with an active certification status
Experience as either a Chief Information Security Officer of an enterprise organization or as a direct report to a Chief Information Security Officer of a large international organization is required
Experience in the attraction, recruitment, hiring, retention and professional development of a diverse team of dedicated information security professionals
Experience in the successful evolution of an information security program
Experience in the evaluation and implementation of industry standard enterprise-wide information security technologies and concepts, including but not limited to: Data Loss Prevention, Security Information and Event Management, Governance, Risk and Compliance Tools, Threat and Vulnerability Management, Identity and Access Management, Application Security, Cloud Security and Computer Forensics
A demonstrated understanding of the complex and diverse threats that an internationally renowned organization with sensitive data can be exposed to
Experience in managing relationships with external information security technology vendors, and specialized information security professional services firms, including management of the evaluation process of their capabilities, and the eventual negotiation of fair service level agreements and contracts between their company and these entities
Must be eligible to obtain security clearance if necessary

Benefits

Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.

Company

Mayo Clinic

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MayoClinic is a nonprofit medical practice and medical research group focused on integrated health care, education, and research.

H1B Sponsorship

Mayo Clinic has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (580)
2024 (476)
2023 (491)
2022 (509)
2021 (389)
2020 (583)

Funding

Current Stage
Late Stage
Total Funding
$399.05M
Key Investors
The ALS AssociationNational Institute of Neurological Disorders and StrokeAmerican Heart Association
2025-12-04Grant· $0.95M
2024-09-24Grant· $12M
2023-07-26Grant

Leadership Team

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Gianrico Farrugia
President and CEO
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Richard Gray
Chief Executive Officer
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Company data provided by crunchbase