PTC Therapeutics, Inc. · 18 hours ago
Scientist I, DMPK
USA - New Jersey - Bridgewater
Full-time
Onsite
Entry Level
$111K/yr - $133K/yr
3+ years expPTC Therapeutics is a global commercial biopharmaceutical company committed to extending life’s moments for those living with rare diseases. The Scientist I, DMPK will be responsible for planning and performing in vitro ADME assays and collaborating with cross-functional teams to support drug discovery activities.
BiotechnologyHealth CareTherapeutics
Responsibilities
With limited guidance, plans, initiates and executes DMPK studies and interprets and communicates results as part of a multi-disciplinary team
Performs hands-on in vitro drug metabolism assays, including solubility, plasma protein binding, tissue binding, B/P ratio, LogD/LogP/pKa measurement, and metabolic stability, etc
Develops and implements bioanalytical methods (LC-MS/MS)
Collaborates with discovery teams to design and conduct in vitro drug metabolism assays
Interprets and presents data/results to internally and externally in cross-functional teams
Documents experiment details in laboratory notebook and writes reports
Ensures the scientific quality of the experimental data
May provide oversight, and/or lead interactions with, the external Contract Research Organizations (CROs)
Abides by all safety and regulatory guidelines
Contributes to general lab needs such as: Equipment maintenance, Troubleshoot
Performs other tasks and assignments as needed and specified by management
Qualification
Required
Hands-on experience in in vitro ADME screening assays
Knowledge of drug metabolism in discovery preclinical research
Knowledge in the principles of LC-MS/MS based small molecule bioanalysis
Experience in developing protocols and writing study reports
Ability to work on complex problems to produce experimental data across one or more projects
Ability to work independently and collaboratively in a fast-paced, matrixed, team environment consisting of internal and external team members
Ability to work effectively in a multi-disciplinary team environment
Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines
Proficiency with Microsoft Office
Excellent verbal and written communication skills
Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects
PhD in biology, pharmaceutical science, pharmacology, or other related scientific discipline OR a Master's degree in these same disciplines and a minimum of 3 years of experience in drug metabolism in a pharmaceutical, biotechnology or related environment
Preferred
Hands on experience in operating and general troubleshooting of contemporary LC-MS instruments and automated liquid handlers
Hands on experience with cell cultures
Benefits
Short- and long-term incentives
Medical, dental, vision, and retirement savings plans
Company
PTC Therapeutics, Inc.
PTC is a patient-centered biopharmaceutical company focused on discovering, developing & commercializing medicine for children and adults living with rare and serious disease.
501-1000 employees
H1B Sponsorship
PTC Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (9)
2023 (14)
2022 (31)
2021 (13)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$1.57BKey Investors
Brookside CapitalCredit Suisse First Boston
2022-10-27Post Ipo Equity· $1B
2020-05-14Post Ipo Equity· $140.95M
2015-08-14Post Ipo Debt· $150M
Leadership Team
Matthew B. Klein
Chief Executive Officer and President
Stuart Peltz
CEO
Recent News
2026-01-12
2026-01-09
Company data provided by crunchbase