Sr. Systems Engineer jobs in United States
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BEPC Inc. - Business Excellence Professional Consulting · 1 day ago

Sr. Systems Engineer

BEPC Inc. is seeking a highly motivated Senior Systems Engineer to support end-to-end solution integration for next-generation diagnostic systems. This role involves hands-on collaboration and focuses on the feasibility, development, and integration of complex systems spanning wet-lab workflows, instrumentation, and bioinformatics/data processing pipelines.

BiotechnologyConsulting
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Diversity & Inclusion
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H1B Sponsor Likelynote
Hiring Manager
Paola Borrero
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Responsibilities

Drive system-level development and integration across:
Sample preparation
Library preparation
Molecular detection technologies (e.g., sequencing, digital PCR, microarrays)
Data processing and bioinformatics pipelines
Perform hands-on system integration and troubleshooting across wet lab workflows and instrumentation
Partner with assay, software, hardware, and bioinformatics teams to ensure seamless end-to-end workflow integration
Contribute to system architecture and requirements definition
Apply statistical analysis and Design of Experiments (DoE) methodologies (e.g., JMP, ANOVA, regression) to optimize system performance and define specifications
Plan, design, and execute verification and validation (V&V) test cases
Analyze test results for accuracy, validity, and relevance to user needs
Support post-launch troubleshooting and field investigations
Conduct failure mode analysis and root cause investigations
Represent Systems Engineering in cross-functional project teams
Collaborate closely with assay scientists, software developers, hardware engineers, and bioinformaticians
Contribute to system documentation including requirements, specifications, integration plans, and V&V reports
Identify and lead opportunities for workflow simplification, automation, and continuous improvement
Influence technical decisions without formal people management responsibilities

Qualification

Systems EngineeringSequencing workflowsStatistical toolsBioinformatics pipelinesPythonDigital PCR platformsIn-vitro diagnosticsAnalytical skillsProblem-solving skillsCommunication skills

Required

Degree in Systems Engineering, Bioengineering, Biomedical Engineering, or related field
One of the following: PhD with 5+ years of relevant industry experience
Master's degree with 10+ years of relevant industry experience
Bachelor's degree with 10+ years of relevant industry experience
Hands-on industry experience with sequencing-related workflows, including: Nucleic acid extraction, Library preparation, Sequencing
Proven lab troubleshooting experience in sequencing and PCR-based workflows
Required experience with statistical tools and DoE methodologies (JMP, regression, ANOVA)
Strong analytical, problem-solving, and systems-thinking skills
Excellent written and verbal communication skills
Ability to work independently while influencing cross-functional teams

Preferred

Exposure to bioinformatics and sequencing data pipelines (variant calling, QC)
Experience with life sciences instrumentation product development
Experience across multiple product lifecycle stages
Experience with: Digital PCR platforms
In-vitro diagnostic (IVD) product development
Semiconductor-based sensing or microfluidic devices
Scripting or programming experience (Python, R, or similar)

Company

BEPC Inc. - Business Excellence Professional Consulting

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BEPC Incorporated provides Technical Engineering and Information Technology Project Management services to Fortune 500 companies in the industries: Life Science, Engineering, Manufacturing, Information Technologies, Advanced Technologies, Automotive, and Construction.

H1B Sponsorship

BEPC Inc. - Business Excellence Professional Consulting has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (3)
2020 (3)

Funding

Current Stage
Growth Stage

Leadership Team

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Oscar Casillas
President and CEO
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Andrew Casillas
Human Resources Partner
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Company data provided by crunchbase